In what could be an early step toward new treatments for people with osteoporosis, scientists at Michigan State University report that a natural probiotic supplement can help male mice produce healthier bones.
Interestingly, the same can’t be said for female mice, the researchers report in the Journal of Cellular Physiology.
“We know that inflammation in the gut can cause bone loss, though it’s unclear exactly why,” said lead author Laura McCabe, a professor in MSU’s departments of Physiology and Radiology. “The neat thing we found is that a probiotic can enhance bone density.” (more…)
UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a stress-response protein in all cells that come under stress instead expresses the protein only in specific cell types.
The research team, from the Jules Stein Eye Institute at UCLA and the UCLA Division of Pulmonary and Critical Care Medicine, focused on αB-Crystallin, one of a class of molecules known as heat shock proteins, which are involved in the folding and unfolding of other proteins, helping them recover from stress so they can do their job. (more…)
About the video: watch an animation showing the changes in the structure of a T7 virus as it infects an E. coli bacterium.
AUSTIN, Texas — The detailed changes in the structure of a virus as it infects an E. coli bacterium have been observed for the first time, report researchers from The University of Texas at Austin and The University of Texas Health Science Center at Houston (UT Health) Medical School this week in Science Express. (more…)
Misguided killer T cells may be the missing link in sustained tissue damage in the brains and spines of people with multiple sclerosis, findings from the University of Washington reveal. Cytoxic T cells, also known as CD8+ T cells, are white blood cells that normally are in the body’s arsenal to fight disease.
Multiple sclerosis is characterized by inflamed lesions that damage the insulation surrounding nerve fibers and destroy the axons, electrical impulse conductors that look like long, branching projections. Affected nerves fail to transmit signals effectively. (more…)
UCLA researchers have discovered a type of cell that is the “missing link” between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy immune system is produced and how disease can lead to poor immune function.
The research was done using human bone marrow, which contains all the stem cells that produce blood during post-natal life. (more…)
Newly described teen literature genre propagates negative portrayals of the sick and disabled
COLUMBIA, Mo. — A newly defined genre of literature, “teen sick-lit,” features tear-jerking stories of ill adolescents developing romantic relationships. Although “teen sick-lit” tends to adhere to negative stereotypes of the ill and traditional gender roles, it also explores the taboo realm of sexuality, sickness and youth, says the University of Missouri researcher who named the genre in a recent study. Readers and their parents should be aware of how the presentation of disease and disability in these stories can instill prejudices and enforce societal norms in young adults, notes the researcher.
“Teen sick-lit depicts its chronically ill protagonists, who are usually white middle-class females, merely as vehicles for well people’s emotional development rather than as self-actualized women with their own experiences, perspectives, and emotional needs,” said Julie Passanante Elman, assistant professor in women’s and gender studies in the College of Arts and Science. “As the popularity of fiction aimed at young adults, such as the Twilight, Harry Potter and Hunger Games series, continues to grow, it is important for readers and parents to note the ethical subtexts of the books. Similarly, the proliferation of sick or disabled characters on such television shows as “Glee,” “Friday Night Lights” and “Breaking Bad” doesn’t always equate to positive portrayals of those characters.” (more…)
EAST LANSING, Mich. — A parasite thought to be harmless and found in many people may actually be causing subtle changes in the brain, leading to suicide attempts.
New research appearing in the August issue of The Journal of Clinical Psychiatry adds to the growing work linking an infection caused by the Toxoplasma gondii parasite to suicide attempts. Michigan State University’s Lena Brundin was one of the lead researchers on the team.
About 10-20 percent of people in the United States have Toxoplasma gondii, or T. gondii, in their bodies, but in most it was thought to lie dormant, said Brundin, an associate professor of experimental psychiatry in MSU’s College of Human Medicine. In fact, it appears the parasite can cause inflammation over time, which produces harmful metabolites that can damage brain cells. (more…)
UCLA study also finds that mindfulness technique benefits immune system
Many elderly people spend their last years alone. Spouses pass and children scatter. But being lonely is much more than a silent house and a lack of companionship. Over time, loneliness not only takes a toll on the psyche but can have a serious physical impact as well.
Feeling lonely has been linked to an increased risk of heart disease, Alzheimer’s disease, depression and even premature death. Developing effective treatments to reduce loneliness in older adults is essential, but previous treatment efforts have had limited success. (more…)
