West Africa, sub-Saharan Africa and South East Asia are most at risk from bat viruses ‘spilling over’ into humans resulting in new emerging diseases, according to a new global map compiled by scientists at UCL, the Zoological Society of London (ZSL) and the University of Edinburgh. (more…)
Research tracks relationships between CEO greed and company performance
That gut feeling many workers, laborers and other underlings have about their CEOs is spot on, according to three recent studies in the Journal of Management, the Journal of Management Studies and the Journal of Leadership and Organizational Studies that say CEO greed is bad for business. (more…)
Michigan State University researchers have identified a genetic mutation in Doberman pinschers that causes albinism in the breed, a discovery that has eluded veterinarians and breeders worldwide up until now.
Paige Winkler, a doctoral student in the College of Veterinary Medicine, co-led the study with Joshua Bartoe, an assistant professor in the Department of Small Animal Clinical Sciences, and discovered a mutated gene that is associated with a form of albinism in humans. (more…)
ANN ARBOR — A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.
By studying zebrafish embryo skin, University of Michigan researchers decoded cell messages underlying abnormal colonic cell growth of the kind that can lead to tumors and colon cancer in calcium deficient individuals. They have also tested this new mechanism in human colon cancer cells. (more…)
Opening the door to more sophisticated investigation of sperm locomotion and biophysics, researchers from UCLA’s Henry Samueli School of Engineering and Applied Science have identified previously unobserved swimming patterns in human and horse sperm cells.
This research, published in Scientific Reports, a journal of the Nature Publishing Group, could lead to a deeper understanding of how sperm move on their way to fertilization or other functions and how they react when encountering various toxins or chemicals. (more…)
TORONTO, ON – University of Toronto Faculty of Medicine researchers have uncovered a genetic basis for fundamental differences between humans and other vertebrates that could also help explain why humans are susceptible to diseases not found in other species.
Scientists have wondered why vertebrate species, which look and behave very differently from one another, nevertheless share very similar repertoires of genes. For example, despite obvious physical differences, humans and chimpanzees share a nearly identical set of genes. (more…)
Paper describes new method to understand sources of noise in gene-expression
Abhyudai Singh, assistant professor of electrical and computer engineering at the University of Delaware, describes a new method to understand sources of “noise” in gene-expression that create variability in protein levels in a paper published in Molecular Systems Biology, a publication of Nature, on Aug. 28.
This noise is expressed as variability in the levels of proteins/mRNAs in a cell. (more…)
Doctors can improve treatment programs using this knowledge
COLUMBIA, Mo. – The human immunodeficiency virus (HIV) can contain dozens of different mutations, called polymorphisms. In a recent study an international team of researchers, including University of Missouri scientists, found that one of those mutations, called 172K, made certain forms of the virus more susceptible to treatment. Soon, doctors will be able to use this knowledge to improve the drug regimen they prescribe to HIV-infected individuals.
“The 172K polymorphism makes certain forms of HIV less resistant to drugs,” said Stefan Sarafianos, corresponding author of the study and a researcher at MU’s Bond Life Sciences Center. “172K doesn’t affect the virus’ normal activities. In some varieties of HIV that have developed resistance to drugs, when the 172K mutation is present, resistance to two classes of anti-HIV drugs is suppressed. We estimate up to 3 percent of HIV strains carry the 172K polymorphism.” (more…)
