Tag Archives: aydogan ozcan

UCLA engineers first to detect and measure individual DNA molecules using smartphone microscope

Lightweight, compact device converts an ordinary smartphone into an advanced fluorescence microscope

Fluorescence microscopes use technology that enables them to accomplish tasks not easy to achieve with normal light microscopes, including imaging DNA molecules to detect and diagnose cancer, nervous system disorders such as Alzheimer’s disease, and drug resistance in infectious diseases. (more…)

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UCLA researchers create Google Glass app for instant medical diagnostic test results

A team of researchers from UCLA’s Henry Samueli School of Engineering and Applied Science has developed a Google Glass application and a server platform that allow users of the wearable, glasses-like computer to perform instant, wireless diagnostic testing for a variety of diseases and health conditions.

With the new UCLA technology, Google Glass wearers can use the device’s hands-free camera to capture pictures of rapid diagnostic tests (RDTs), small strips on which blood or fluid samples are placed and which change color to indicate the presence of HIV, malaria, prostate cancer or  other conditions. Without relying on any additional devices, users can upload these images to a UCLA-designed server platform and receive accurate analyses — far more detailed than with the human eye — in as little as eight seconds. (more…)

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UCLA researchers discover sperm move along a ‘twisting ribbon’

Opening the door to more sophisticated investigation of sperm locomotion and biophysics, researchers from UCLA’s Henry Samueli School of Engineering and Applied Science have identified previously unobserved swimming patterns in human and horse sperm cells.

This research, published in Scientific Reports, a journal of the Nature Publishing Group, could lead to a deeper understanding of how sperm move on their way to fertilization or other functions and how they react when encountering various toxins or chemicals. (more…)

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UCLA’s New Nano-Lens Microscopes Can Detect Viruses, Other Objects at Nanoscale

By using tiny liquid lenses that self-assemble around microscopic objects, a team from UCLA’s Henry Samueli School of Engineering and Applied Science has created an optical microscopy method that allows users to directly see objects more than 1,000 times smaller than the width of a human hair.

Coupled with computer-based computational reconstruction techniques, this portable and cost-effective platform, which has a wide field of view, can detect individual viruses and nanoparticles, making it potentially useful in the diagnosis of diseases in point-of-care settings or areas where medical resources are limited. (more…)

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Got Food Allergies? Thanks to UCLA, You Can Test Your Meal on the Spot Using a Cell Phone

Are you allergic to peanuts and worried there might be some in that cookie? Now you can find out using a rather unlikely source: your cell phone.

A team of researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a lightweight device called the iTube, which attaches to a common cell phone to detect allergens in food samples. The iTube attachment uses the cell phone’s built-in camera, along with an accompanying smart-phone application that runs a test with the same high level of sensitivity a laboratory would. (more…)

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UCLA Engineers Shed New Light on 3-D Motion of Human Sperm Cells

Using new lensless imaging platform, team observes rare helical movements

A team of researchers from the UCLA Henry Samueli School of Engineering and Applied Science has, for the first time, directly recorded the three-dimensional helical swimming patterns of human sperm cells.

The team, led by Aydogan Ozcan, associate professor of electrical engineering and bioengineering, developed a novel lensless computational imaging platform that accurately tracked more than 24,000 individual sperm cells in a large volume. This involved observing the individual rotations of each sperm cell, including helical movement patterns, rotation speed, and linear and curved distances traveled. (more…)

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