Tag Archives: H1N1

‘Core’ immune cells reduce symptoms and spread of flu

A four-year study of 1,414 unvaccinated people across England found that 43% of them had immune cells that protected them from symptoms of both seasonal and pandemic influenza, and reduced their chances of shedding the virus by two thirds. The work led by researchers from UCL, Oxford University and Public Health England was funded by the Medical Research Council and Wellcome Trust. (more…)

Read More

Predicting hotspots for future flu outbreaks

This year’s unusually long and rocky flu season would be nothing compared to the pandemic that could occur if bird flu became highly contagious among humans, which is why UCLA researchers and their colleagues are creating new ways to predict where an outbreak could emerge.

“Using surveillance of influenza cases in humans and birds, we’ve come up with a technique to predict sites where these viruses could mix and generate a future pandemic,” said lead author Trevon Fuller, a UCLA postdoctoral research fellow at the Institute of the Environment and Sustainability’s Center for Tropical Research. (more…)

Read More

UCLA’s New Nano-Lens Microscopes Can Detect Viruses, Other Objects at Nanoscale

By using tiny liquid lenses that self-assemble around microscopic objects, a team from UCLA’s Henry Samueli School of Engineering and Applied Science has created an optical microscopy method that allows users to directly see objects more than 1,000 times smaller than the width of a human hair.

Coupled with computer-based computational reconstruction techniques, this portable and cost-effective platform, which has a wide field of view, can detect individual viruses and nanoparticles, making it potentially useful in the diagnosis of diseases in point-of-care settings or areas where medical resources are limited. (more…)

Read More

A SMART(er) Way to Track Influenza

Brown University researchers have created a reliable and fast flu-detection test that can be carried in a first-aid kit. The novel prototype device isolates influenza RNA using a combination of magnetics and microfluidics, then amplifies and detects probes bound to the RNA. The technology could lead to real-time tracking of influenza. Results are published in the Journal of Molecular Diagnostics.

PROVIDENCE, R.I. [Brown University] — In April 2009, the world took notice as reports surfaced of a virus in Mexico that had mutated from pigs and was being passed from human to human. The H1N1 “swine flu,” as the virus was named, circulated worldwide, killing more than 18,000 people, according to the World Health Organization. The Centers for Disease Control and Prevention in the United States said it was the first global pandemic in more than four decades. (more…)

Read More

Powerful New Approach to Attack Flu Virus

EAST LANSING, Mich. — An international research team has manufactured a new protein that can combat deadly flu epidemics.

The paper, featured on the cover of the current issue of Nature Biotechnology, demonstrates ways to use manufactured genes as antivirals, which disable key functions of the flu virus, said Tim Whitehead, assistant professor of chemical engineering and materials science at Michigan State University.

“Our most potent design has proven effective on the vulnerable sites on many pandemic influenza viruses, including several H1N1 (Spanish flu, Swine flu) and H5N1 (Avian flu) subtypes,” said Whitehead, the paper’s co-lead author. “These new therapeutics are urgently needed, so we were especially pleased to see that it neutralizes H1N1 viruses with potency.” (more…)

Read More

UCLA Scientists Find H1N1 Flu Virus Prevalent in Animals in Africa

UCLA life scientists and their colleagues have discovered the first evidence of the H1N1 virus in animals in Africa. In one village in northern Cameroon, a staggering 89 percent of the pigs studied had been exposed to the H1N1 virus, commonly known as the swine flu.

“I was amazed that virtually every pig in this village was exposed,” said Thomas B. Smith, director of UCLA’s Center for Tropical Research and the senior author of the research. “Africa is ground zero for a new pandemic. Many people are in poor health there, and disease can spread very rapidly without authorities knowing about it.” (more…)

Read More