Tag Archives: electron microscopy

UCLA’s New Nano-Lens Microscopes Can Detect Viruses, Other Objects at Nanoscale

By using tiny liquid lenses that self-assemble around microscopic objects, a team from UCLA’s Henry Samueli School of Engineering and Applied Science has created an optical microscopy method that allows users to directly see objects more than 1,000 times smaller than the width of a human hair.

Coupled with computer-based computational reconstruction techniques, this portable and cost-effective platform, which has a wide field of view, can detect individual viruses and nanoparticles, making it potentially useful in the diagnosis of diseases in point-of-care settings or areas where medical resources are limited. (more…)

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Berkeley Lab Scientists Create First 3-D Model of a Protein Critical to Embryo Development

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab). Knowing the architecture of this protein,  PRC2, for Polycomb Repressive Complex 2, should be a boon to its future use in the development of new and improved therapeutic drugs.

“We present a complete molecular organization of human PRC2 that offers an invaluable structural context for understanding all of the previous biochemical and functional data that has been collected on this complex,” says Berkeley Lab biophysicist Eva Nogales, an electron microscopy expert who led this research. “Our model should also be an invaluable tool for the design of new experiments aimed at asking detailed questions about the mechanisms that enable PRC2 to function and how those mechanisms might be exploited.” (more…)

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Chemists Advance Clear Conductive Films

Thin, conductive films are useful in displays and solar cells. A new solution-based chemistry developed at Brown University for making indium tin oxide films could allow engineers to employ a much simpler and cheaper manufacturing process.

PROVIDENCE, R.I. [Brown University] — In a touch-screen display or a solar panel, any conductive overlay had better be clear. Engineers employ transparent thin films of indium tin oxide (ITO) for the job, but a high-tech material’s properties are only half its resume. They must also be as cheap and easy to manufacture as possible. In a new study, researchers from Brown University and ATMI Inc. report the best-ever transparency and conductivity performance for an ITO made using a chemical solution, which is potentially the facile, low-cost method manufacturers want.

“Our technology is already at the performance level for application in resistive touch screens,” said Jonghun Lee, a Brown chemistry graduate student and lead author of the paper posted online Aug. 1 by the Journal of the American Chemical Society. (more…)

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Yale Research Reveals Ancient Moth’s True Colors

A research team led by Yale University scientists has for the first time determined the original colors of an ancient moth, based on nearly 50 million-year-old fossils from Germany.

The discovery could help scientists learn the colors of a wide variety of long-extinct creatures, including birds, fishes, and other insects, and shed light on color’s function and evolution. (more…)

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