Fats spur cells to divide faster, promoting tumor growth
New UCLA research could help explain the link between a high-cholesterol diet and an elevated risk for colon cancer. (more…)
ANN ARBOR — A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.
By studying zebrafish embryo skin, University of Michigan researchers decoded cell messages underlying abnormal colonic cell growth of the kind that can lead to tumors and colon cancer in calcium deficient individuals. They have also tested this new mechanism in human colon cancer cells. (more…)
Drug efficiently targets breast, lung and colon cancer; clinical trials could start within two years.
COLUMBIA, Mo. — Legend has it that Ralph Waldo Emerson once said, “Build a better mousetrap, and the world will beat a path to your door.” University of Missouri researchers are doing just that, but instead of building mousetraps, the scientists are targeting cancer drugs. In a new study, MU medicinal chemists have taken an existing drug that is being developed for use in fighting certain types of cancer, added a special structure to it, and created a more potent, efficient weapon against cancer.
“Over the past decade, we have seen an increasing interest in using carboranes in drug design,” said Mark W. Lee Jr., assistant professor of chemistry in College of Arts and Science. “Carboranes are clusters of three elements — boron, carbon and hydrogen. Carboranes don’t fight cancer directly, but they aid in the ability of a drug to bind more tightly to its target, creating a more potent mechanism for destroying the cancer cells.” (more…)
EAST LANSING, Mich. — Researchers at Michigan State University have shown a prebiotic may help the body’s own natural killer cells fight bacterial infection and reduce inflammation, greatly decreasing the risk of colon cancer.
Prebiotics are fiber supplements that serve as food for the trillions of tiny bacteria living in the gut. When taken, they can stimulate the growth of the “good” bacteria. The evolution of prebiotic supplements (as well as probiotics, which are actual bacteria ingested into the system) provide new therapeutic targets for researchers and physicians. (more…)
In the coming days a historic event can happen in Cuba. The leader of the revolution, 84-year-old Fidel Castro is likely to leave the last of his posts as the leader of the Communist Party of Cuba.
According to a source in the Cuban party elite, the organization will be headed by the 79-year-old brother of the Comandante Raul Castro. So far, he served as the second secretary of the party. It is assumed that the legal registration of the changes in the party leadership will occur in April. At the same time it is not clear who will be the second secretary in place of Raul. There are no candidates among the relatives of the legendary brothers. (more…)
*Researchers urge appropriate use of androgen deprivation therapy*
ANN ARBOR, Mich. — Men treated with hormone-based therapy for prostate cancer faced a 30 percent to 40 percent higher risk of colorectal cancer, compared to patients who did not receive this treatment, according to a new study.
The study looked at use of androgen deprivation therapy, a common type of treatment for prostate cancer that involves blocking the male hormone testosterone through either surgical removal of the testicles or a series of injections. It’s been shown to benefit men with advanced cancers, but its benefit for less-advanced disease is unclear. Still, more than half a million men in the United States currently receive this therapy. (more…)
