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Building Healthy Bones Takes Guts

By Guest PostFebruary 22, 2013Health, Scienceamericans, bacterium, balance, begins at childhood, bone density, bone fractures, bone loss, bone tissue, cellular physiology, chronic condition, coevolved with humans, female mice, food fermentation, gut, harmful effect, healthier bones, immune system, infection, inflammation, inflammatory bowel disease, joint, laura mccabe, laura schaefer, male mice, mice lactobacillus reuteri, michigan state university, microorganisms, muscle pain, natural probiotic supplement, natural remodeling, negative side effects, osteoporosis, osteoporosis drugs, postmenopausal women, regina irwin, robert britton, species, treatments, type 1 diabetes

In what could be an early step toward new treatments for people with osteoporosis, scientists at Michigan State University report that a natural probiotic supplement can help male mice produce healthier bones.

Interestingly, the same can’t be said for female mice, the researchers report in the Journal of Cellular Physiology.

“We know that inflammation in the gut can cause bone loss, though it’s unclear exactly why,” said lead author Laura McCabe, a professor in MSU’s departments of Physiology and Radiology. “The neat thing we found is that a probiotic can enhance bone density.” (more…)

Researchers Show Prebiotic Can Reduce Severity of Colitis

By Guest PostMay 4, 2012Healthbacterial infection, cells, colitis, colon cancer, elizabeth gardner, fiber supplements, galacto oligosaccharide, good bacteria, gos, gut, inflammation, inflammatory bowel disease, intestinal ailments, jenifer fenton, michigan state university, natural killer, prebiotic, probiotics, synthetic compound

EAST LANSING, Mich. — Researchers at Michigan State University have shown a prebiotic may help the body’s own natural killer cells fight bacterial infection and reduce inflammation, greatly decreasing the risk of colon cancer.

Prebiotics are fiber supplements that serve as food for the trillions of tiny bacteria living in the gut. When taken, they can stimulate the growth of the “good” bacteria. The evolution of prebiotic supplements (as well as probiotics, which are actual bacteria ingested into the system) provide new therapeutic targets for researchers and physicians. (more…)

Gut Microbe Networks Differ From Norm in Obese People, Systems Biology Approach Reveals

By Guest PostJanuary 13, 2012Scienceabundance of enzymes, alfred p sloan foundation, biomarkers, body weight, building blocks of proteins, cohesive system, disease resistance, elhanan borenstein, energy, gene set, gut, habitats, human anatomy, human body, human genes, human gut, human host, human microbiome, immunity and nutrition, in silico modeling, inflammatory bowel disease, integrated biological system, microbes, microorganism, modeled network, modularity, multiple microbial species, organism, periphery, peter j turnbaugh, sharon greenblum, species, supra organism, university of washington, vitamins

For the first time, researchers have analyzed the multitude of microorganisms residing in the human gut as a complex, integrated biological system, rather than a set of separate species. Their approach has revealed patterns that correspond with excess body weight.

The senior author of the paper, Elhanan Borenstein, assistant professor of genome sciences at the University of Washington, said, “Our research introduces a novel framework, applying systems biology and in-silico (computer) modeling to study the human microbiome – the complex ensemble of microorganisms that populate the human body – as a single cohesive system.” (more…)

Tag Archives: inflammatory bowel disease

Building Healthy Bones Takes Guts

Researchers Show Prebiotic Can Reduce Severity of Colitis

Gut Microbe Networks Differ From Norm in Obese People, Systems Biology Approach Reveals