Tag Archives: immune system

Immune system, brain and behavior

Researchers find prenatal infection may create risk for later disorders

The Zika virus now active in numerous countries, and the severe birth defects associated with it, makes it clear that infection in pregnant women can have immediate and devastating effects on the developing baby. (more…)

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Ancient ‘genomic parasites’ spurred evolution of pregnancy in mammals

Study identifies thousands of genes that were turned on or off in the uterus during the evolution of pregnancy

An international team of scientists has identified large-scale genetic changes that marked the evolution of pregnancy in mammals. (more…)

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Viruses: Tiny Teachers of Biology

Imagine that an invisible, microscopic invader has found its way into your body and hijacked the cellular machinery that keeps you healthy. Inhabiting the gray area between living and nonliving, the invader can only reproduce once it makes its new home inside of your cells, eventually causing you to fall ill. How do physicians and scientists combat this uninvited guest? (more…)

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Molecular map reveals genetic origins of 21 autoimmune diseases

Scientists have created a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, they report Oct. 27 in the journal Nature.

Researchers at Yale, the University of California-San Francisco (UCSF), and the Broad Institute of MIT and Harvard developed a sophisticated mathematical model and created maps of different cell types that together enabled them to identify which variants cause the immune response to go awry and cause specific diseases. (more…)

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Decoding dengue and West Nile: Researchers take steps toward control of growing public health problems

ANN ARBOR — Dengue fever and West Nile fever are mosquito-borne diseases that affect hundreds of millions of people worldwide each year, but there is no vaccine against either of the related viruses.

A team of scientists at the University of Michigan and Purdue University has discovered a key aspect both to how the viruses replicate in the cells of their host and how they manipulate the immune system as they spread. (more…)

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How a Concussion Can Lead to Depression Years Later

After brain injury, cells on ‘high alert’ prolong immune response, affecting behavior

COLUMBUS, Ohio – A head injury can lead immune-system brain cells to go on “high alert” and overreact to later immune challenges by becoming excessively inflammatory – a condition linked with depressive complications, a new animal study suggests.

The findings could help explain some of the midlife mental-health issues suffered by individuals who experience multiple concussions as young adults, researchers say. And these depressive symptoms are likely inflammation-related, which means they may not respond to common antidepressants. (more…)

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IBM Research and Institute of Bioengineering and Nanotechnology Convert Recycled Plastics into Disease Fighting Nanofibers

Opens new applications for the nearly 5.5 billion pounds of PET bottles and jars available annually for recycling

SAN JOSE, Calif – 09 Dec 2013: Researchers from IBM and the Institute of Bioengineering and Nanotechnology have made a nanomedicine breakthrough in which they converted common plastic materials like polyethylene terephthalate (PET) into non-toxic and biocompatible materials designed to specifically target and attack fungal infections. This research was published today in the peer-reviewed journal, Nature Comm. (more…)

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