Tag Archives: autoimmune diseases

Molecular map reveals genetic origins of 21 autoimmune diseases

Scientists have created a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, they report Oct. 27 in the journal Nature.

Researchers at Yale, the University of California-San Francisco (UCSF), and the Broad Institute of MIT and Harvard developed a sophisticated mathematical model and created maps of different cell types that together enabled them to identify which variants cause the immune response to go awry and cause specific diseases. (more…)

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Yale Researchers Identify Salt as a Trigger of Autoimmune Diseases

For the past few decades, health officials have been reporting increases in the incidence of autoimmune diseases such as multiple sclerosis (MS). Now researchers at Yale Medical School, Harvard Medical School and the Broad Institute have identified a prime suspect in the mystery — dietary salt.

In the March 6 issue of the journal Nature, Yale researchers showed that salt can induce and worsen pathogenic immune system responses in mice and that the response is regulated by genes already implicated in a variety of autoimmune diseases. (more…)

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Dark Ages Scourge Enlightens Modern Struggle between Man and Microbes

The plague-causing bacteria Yersinia pestis evades detection and establishes a stronghold without setting off the body’s early alarms. New discoveries reported today help explain how the stealthy agent of Black Death avoids tripping a self-destruct mechanism inside germ-destroying cells.

The authors of the study, appearing in the Dec. 13 issue of Cell Host & Microbe, are Dr. Christopher N. LaRock of the University of Washington Department of Microbiology and Dr. Brad Cookson, UW professor of microbiology and laboratory medicine. (more…)

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Why Bad Immunity Genes Survive

*Study implicates “arms race” between genes and germs*

Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs–even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.

“Major histocompatibility complex” (MHC) proteins are found on the surfaces of most cells in vertebrate animals. They distinguish proteins like themselves from foreign proteins, and trigger an immune response against these foreign invaders. (more…)

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Green Tea fights against many evils and wins

Green tea As the old Chinese saying goes by “Better to be deprived of food for three days than tea for one”, obviously pointing to the recent days most researched ‘green tea’ and its medicinal benefits. Green tea is part of Chinese culture for several thousands years.

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