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Molecular map reveals genetic origins of 21 autoimmune diseases

By Guest PostNovember 5, 2014Healthalyssa coyne, anja karliczek, autoimmune diseases, bakterienbildung, cause, david hafler, immune system, isaiah eterno muchilwa, lorenz michel, mais silos, messgeraet, multiple sclerosis, muscle paralysis, pamela anderson, single nucleotide polymorphisms, snps

Scientists have created a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, they report Oct. 27 in the journal Nature.

Researchers at Yale, the University of California-San Francisco (UCSF), and the Broad Institute of MIT and Harvard developed a sophisticated mathematical model and created maps of different cell types that together enabled them to identify which variants cause the immune response to go awry and cause specific diseases. (more…)

Yale Researchers Identify Salt as a Trigger of Autoimmune Diseases

By Guest PostMarch 14, 2013Healthautoimmune diseases, autoimmune encephalomyelitis, aviv regev, david hafler, destructive immune system, dietary salt, disease, dominik mueller, Environment, function, gene, Germany, hallmark of autoimmunity, high salt content, hypertension, immune cell, low fat diet, low salt, molecular circuitry, ms, multiple sclerosis, mystery, Nature, pathogenic th17 cells, prime suspect, sub-saharan africa, t helper 17, th17 cell, vijay kuchroo

For the past few decades, health officials have been reporting increases in the incidence of autoimmune diseases such as multiple sclerosis (MS). Now researchers at Yale Medical School, Harvard Medical School and the Broad Institute have identified a prime suspect in the mystery — dietary salt.

In the March 6 issue of the journal Nature, Yale researchers showed that salt can induce and worsen pathogenic immune system responses in mice and that the response is regulated by genes already implicated in a variety of autoimmune diseases. (more…)

Why Bad Immunity Genes Survive

By Guest PostFebruary 10, 2012Health, Scienceankylosing spondylitis, antagonistic co evolution, antibiotics, arms race, autoimmune diseases, bacteria, cells, cornelius whitney hyzer, gene, genetics, george gilchrist, germs, immune system, infection, infectious diseases, james ruff, jason kubinak, major histocompatibility complex, mhc, mhc variants, mhcs, mice, national science foundation, parasite, pathogens, patricia slev, people, protein, university of utah, variant, vertebrate animals, virus, wayne potts

*Study implicates “arms race” between genes and germs*

Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs–even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.

“Major histocompatibility complex” (MHC) proteins are found on the surfaces of most cells in vertebrate animals. They distinguish proteins like themselves from foreign proteins, and trigger an immune response against these foreign invaders. (more…)

Green Tea fights against many evils and wins

By ShamsDecember 20, 20073 commentsHealthanti-oxidant, autoimmune diseases, catechin, green tea, Medical College of Georgia, prostate cancer, rheumatoid arthritis, Sjogren’s Syndrom

As the old Chinese saying goes by “Better to be deprived of food for three days than tea for one”, obviously pointing to the recent days most researched ‘green tea’ and its medicinal benefits. Green tea is part of Chinese culture for several thousands years.

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Tag Archives: autoimmune diseases

Molecular map reveals genetic origins of 21 autoimmune diseases

Yale Researchers Identify Salt as a Trigger of Autoimmune Diseases

Why Bad Immunity Genes Survive

Green Tea fights against many evils and wins