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UA Researchers Pinpoint Pathway to Muscle Paralysis

Researchers have discovered a key player in the molecular process that causes the communication breakdown between nerves in fatal muscle degeneration disease.

Researchers at the University of Arizona have taken an essential step forward in the quest to find the cause of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease. In the cells of flies, mice and humans with ALS, scientists at the UA have pinpointed a process that collapses when a critical protein’s blueprint is arrested on its way to protein construction. The study was published recently in the journal Cell Reports. (more…)

Molecular map reveals genetic origins of 21 autoimmune diseases

By Guest PostNovember 5, 2014Healthalyssa coyne, anja karliczek, autoimmune diseases, bakterienbildung, cause, david hafler, immune system, isaiah eterno muchilwa, lorenz michel, mais silos, messgeraet, multiple sclerosis, muscle paralysis, pamela anderson, single nucleotide polymorphisms, snps

Scientists have created a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, they report Oct. 27 in the journal Nature.

Researchers at Yale, the University of California-San Francisco (UCSF), and the Broad Institute of MIT and Harvard developed a sophisticated mathematical model and created maps of different cell types that together enabled them to identify which variants cause the immune response to go awry and cause specific diseases. (more…)

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UA Researchers Pinpoint Pathway to Muscle Paralysis

Molecular map reveals genetic origins of 21 autoimmune diseases