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Lifestyle, age linked to diabetes-related protein

By Guest PostSeptember 25, 2013Healthage, asian, atsushi goto, binding globulin, black, bmi, body mass index, brian chen, demographic factors, diabetes related protein, early biomarker, hispanic, jane cauley, lifestyle, metabolic syndrome, nongenetic factors, pacific islander, postmenopausal women, risk, sex hormone, shbg, simin liu, type 2 diabetes, yiqing song

A large, newly published study that includes more than 13,500 postmenopausal women has yielded the most definitive associations yet between certain lifestyle and demographic factors and levels of a promising early biomarker of type 2 diabetes risk.

PROVIDENCE, R.I. [Brown University] — Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance. (more…)

Building Healthy Bones Takes Guts

By Guest PostFebruary 22, 2013Health, Scienceamericans, bacterium, balance, begins at childhood, bone density, bone fractures, bone loss, bone tissue, cellular physiology, chronic condition, coevolved with humans, female mice, food fermentation, gut, harmful effect, healthier bones, immune system, infection, inflammation, inflammatory bowel disease, joint, laura mccabe, laura schaefer, male mice, mice lactobacillus reuteri, michigan state university, microorganisms, muscle pain, natural probiotic supplement, natural remodeling, negative side effects, osteoporosis, osteoporosis drugs, postmenopausal women, regina irwin, robert britton, species, treatments, type 1 diabetes

In what could be an early step toward new treatments for people with osteoporosis, scientists at Michigan State University report that a natural probiotic supplement can help male mice produce healthier bones.

Interestingly, the same can’t be said for female mice, the researchers report in the Journal of Cellular Physiology.

“We know that inflammation in the gut can cause bone loss, though it’s unclear exactly why,” said lead author Laura McCabe, a professor in MSU’s departments of Physiology and Radiology. “The neat thing we found is that a probiotic can enhance bone density.” (more…)

Researchers Discover How Progesterone May Increase Breast Cancer Risk

By Guest PostJanuary 19, 2011Health, Scienceanastasia kariagina, breast cancer, cell growth, epidermal growth factor, estrogen, hormone, hormone dependent, hormone replacement therapy, human breast, mammary cancers, mammary cells, phenomenon, postmenopausal women, progesterone, progestin, protein amphiregulin, risk of breast cancer, sandra haslam, tumor growth

EAST LANSING, Mich. — Researchers have identified how the hormones progesterone and estrogen interact to increase cell growth in normal mammary cells and mammary cancers, a novel finding that may explain why postmenopausal women receiving hormone replacement therapy with estrogen plus progestin are at increased risk of breast cancer.

The discovery that both estrogen and progesterone must be present for the increased production of the protein amphiregulin, which binds to mammary cells and promotes cell growth, could lead to new treatment methods for the disease, said Sandra Haslam, director of Michigan State University’s Breast Cancer and the Environment Research Center and lead researcher on the project. (more…)

Tag Archives: postmenopausal women

Lifestyle, age linked to diabetes-related protein

Building Healthy Bones Takes Guts

Researchers Discover How Progesterone May Increase Breast Cancer Risk