UCLA researchers have discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells — the cells that form blood vessels. The finding could point the way toward a new strategy for treating people who have suffered a heart attack, because increasing the number of blood vessels in the heart boosts its ability to heal after injury. (more…)
The closest supernova of its kind to be observed in the last few decades has sparked a global observing campaign involving legions of instruments on the ground and in space, including NASA’s Spitzer Space Telescope. With its dust-piercing infrared vision, Spitzer brings an important perspective to this effort by peering directly into the heart of the aftermath of the stellar explosion.
Dust in the supernova’s host galaxy M82, also called the “Cigar galaxy,” partially obscures observations in optical and high-energy forms of light. Spitzer can, therefore, complement all the other observatories taking part in painting a complete portrait of a once-in-a-generation supernova, which was first spotted in M82 on Jan. 21, 2014. A supernova is a tremendous explosion that marks the end of life for some stars. (more…)
Early Step toward Treatment for Diseases that Affect Blood Flow
University of Utah bioengineers showed that tiny blood vessels grow better in the laboratory if the tissue surrounding them is less dense. Then the researchers created a computer simulation to predict such growth accurately – an early step toward treatments to provide blood supply to tissues damaged by diabetes and heart attacks and to skin grafts and implanted ligaments and tendons.
“Better understanding of the processes that regulate the growth of blood vessels puts us in a position ultimately to develop new treatments for diseases related to blood vessel growth,” and to better understand cancer metastasis, says bioengineering professor Jeff Weiss of the university’s Scientific Computing and Imaging Institute. (more…)
TORONTO, ON – University of Toronto Faculty of Medicine researchers have uncovered a genetic basis for fundamental differences between humans and other vertebrates that could also help explain why humans are susceptible to diseases not found in other species.
Scientists have wondered why vertebrate species, which look and behave very differently from one another, nevertheless share very similar repertoires of genes. For example, despite obvious physical differences, humans and chimpanzees share a nearly identical set of genes. (more…)
COLUMBUS, Ohio – Taking enough omega-3 fatty acid supplements to change the balance of oils in the diet could slow a key biological process linked to aging, new research suggests.
The study showed that most overweight but healthy middle-aged and older adults who took omega-3 supplements for four months altered a ratio of their fatty acid consumption in a way that helped preserve tiny segments of DNA in their white blood cells. (more…)
Hospitals that continue CPR longer have better survival rates from cardiac arrests, according to a study published online Sept. 5 in The Lancet. The findings challenge the assumption that, if a pulse is not restored soon, continuing resuscitation efforts is futile.
The results also showed that patients who recovered after an extended CPR effort were no more likely to suffer brain damage than are patients revived after a shorter effort. (more…)
UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place on Aug. 9.
Ronald Reagan UCLA Medical Center is part of a growing trend of hospitals nationwide offering this new minimally invasive procedure. (more…)
Researchers have made a major advance in efforts to regenerate damaged hearts. They discovered that transplanted heart muscle cells, grown from stem cells, electrically couple and beat in sync with the heart’s own mucle.
The grafts also reduced the incidence of arrhythmias (irregular heart rhythms) in a guinea pig model of myocardial infarction (commonly known as a heart attack).
This finding from University of Washington-led research is reported in the Aug. 5 issue of Nature. (more…)
