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New algorithm more accurately predicts life expectancy after heart failure

By Guest PostOctober 16, 2018Healthalgorithm, heart failure, heart transplant, life expectancy, trees of predictors

UCLA research could help health care providers make better use of life-saving resources

A new algorithm developed by UCLA researchers more accurately predicts which people will survive heart failure, and for how long, whether or not they receive a heart transplant. The algorithm would allow doctors to make more personalized assessments of people who are awaiting heart transplants, which in turn could enable health care providers to make better use of limited life-saving resources and potentially reduce health care costs. (more…)

Racing the Clock to Help Young Patients with Old Hearts

By Guest PostJuly 11, 2014Healthapc2, army private cloud, biomolekuele als katalysator, cell types, cloud deal, genetically engineered, heart failure, hiatus phenomenon, kohlenstoff molekuele, muscle cells, normaldruck, nullpunkt, paul scheier, protein, schneebaelle, stem cells, stroke, university of maryland, xiao hai yan

UMD study of premature aging may help explain effects of normal aging

COLLEGE PARK, Md. – Children with progeria, a rare disorder that causes premature aging, die in their teens of ailments that are common in octogenarians: heart failure and stroke. Kan Cao, a University of Maryland assistant professor of cell biology and molecular genetics, urgently wants to help find a cure. Cao and her colleagues have taken a big step in that direction, showing that a toxic protein destroys muscle cells inside the patients’ arteries. The researchers suspect the damaged arteries are more prone to failure. (more…)

IBM Predictive Analytics to Detect Patients at Risk for Heart Failure

By Guest PostFebruary 19, 2014Technologycarilion clinic, emrs, heart failure, ibm predictive analytics, patients at risk, sean hogan, steve morgan, virginia health system

Big Data Solution Identifies 8,500 Patients at Risk for Heart Failure Using Insights from Electronic Medical Records

ARMONK, N.Y. – 19 Feb 2014: IBM today announced that Virginia health system Carilion Clinic has indentified 8,500 patients at risk for developing heart failure in a pilot project that could lead to early intervention and better care for these patients. (more…)

Gene therapy may aid failing hearts

By Guest PostApril 4, 2013Health2 deoxy atp, adenosine 5 triphosphate, alya red, american heart association, animal study, atp, barcelona superconducting center, cardiac muscle fibers, charles murry, datp, DNA, electromechanical computational model, embryonic growth, enzyme, failing hearts, gene therapy, heart attacks, heart conditions, heart failure, heart muscle function, mechanically stressed, michael regnier, muscle contraction, nucleotide, university of washington

The potential of gene therapy to boost heart muscle function was explored in a recent University of Washington animal study. The findings suggest that it might be possible to use this approach to treat patients whose hearts have been weakened by heart attacks and other heart conditions.

Michael Regnier, UW professor and vice chair of bioengineering, Charles Murry, director of the Center for Cardiovascular Biology and co-director of the Institute for Stem Cell and Regenerative Medicine, and Sarah Nowakowski, a UW graduate student in bioengineering, led the study. The findings appeared online March 25 in the Proceedings of the National Academy of Sciences. (more…)

UCLA Uses New Device to Replace Aortic Valve in Patients Who Can’t Have Open-Heart Surgery

By Guest PostAugust 19, 2012Healthaortic stenosis, aortic valve, blood flow, calcium deposits, cardiopulmonary bypass, chest wall, heart, heart failure, jonathan tobis, open heart surgery, quality of life, richard j shemin, ronald reagan, tavr, tavr procedure, ucla, ucla medical center, valve replacement

UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place on Aug. 9.

Ronald Reagan UCLA Medical Center is part of a growing trend of hospitals nationwide offering this new minimally invasive procedure. (more…)

Survival Rates Lower for Heart Transplant Patients Whose Arteries Reclose after Stenting

By Guest PostJune 20, 2012Healthclogged artery, heart failure, heart transplant patients, survival rates, transplant patients

Heart transplant patients are notorious for developing an aggressive form of coronary artery disease that can often result in heart failure, death or the need for repeat transplantation. The condition can also have a negative impact on future cardiac procedures, such as stenting. (more…)

Heart Failure Patients with Diabetes May Benefit From Higher Glucose Levels

By Guest PostApril 12, 2012Healthanti diabetic medication, atherosclerosis, blood, blood test, cardiology, diabetes, glucose level, glycosylated hemoglobin, heart failure, heart transplant, hormonal activity, marker, oxidative stress, rachel champeau, sofia tomova, survival rate, tamara horwich, ucla, university of california, vani nimbal, vascular lining dysfunction

Lowering glucose levels for people with diabetes is normally critical to improving health outcomes. But for diabetes patients with heart failure, that might not always be the case, say UCLA researchers.

A new study found that for advanced heart failure patients with diabetes, having higher blood glucose levels may actually help improve survival rates. (more…)

New Study Suggests Link Between Estrogen, Blood Pressure

By Guest PostMay 28, 2011Healthanti oxidant resveratrol, blood pressure, brain, carrie northcutt, chronic exposure, effects of menopause, estrogen only hrt, hannah garver, heart failure, high blood pressure, hormone, huawei zhao, hypertension, joseph haywood, long term exposure to estrogen, madhan subramanian, michigan state university, mohankumar, p s mohankumar, priya balasubramanian, rostral ventrolateral medulla, stress in the body, superoxide, women

EAST LANSING, Mich. — While recent studies have shown long-term exposure to estrogen can be a danger to women – overturning physicians’ long-held beliefs that the hormone was good for their patients’ hearts – the process by which estrogen induces high blood pressure was unclear.

In a new study, Michigan State University researchers found long-term estrogen exposure generates excessive levels of the compound superoxide, which causes stress in the body. The buildup of this compound occurs in an area of the brain that is crucial to regulating blood pressure, suggesting that the estrogen-induced buildup causes increased blood pressure. (more…)

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