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UCLA doctors test stem-cell therapy to improve blood flow in angina patients

By Guest PostNovember 24, 2013Healthali nsair, angina patients, angioplasty, blood flow, cd34 protein, coronary bypass, heart attack, heart in 3d, heart muscle, heart transplant, jonathan tobis, las vegas, marty greenfield, phase 3, pluripotent cell, rubine gevorgyan, stem cell injection, stem cell therapy, ucla doctors, william suh

Clinical trial evaluates treatment for patients who haven’t responded to other FDA–approved procedures

Marty Greenfield lives with crushing pain every day due to angina, a condition that is caused by an inadequate supply of blood to the heart. He has suffered a heart attack, and a coronary bypass procedure and angioplasty have provided little relief. His doctor referred him to UCLA to be considered for a heart transplant.

Dr. Jonathan Tobis, a UCLA clinical professor of cardiology, performed an angiogram and angioplasty on Greenfield, 64, but found that the patient was not a candidate for a heart transplant because his heart muscle function was still good. (more…)

An efficient nectar mop: Bats use blood to reshape tongue for feeding

By Guest PostJune 12, 2013Natureaxis of tongue, bat tongues, blood flow, cylindrical tongue, hemodynamic nectar mop, hummingbird tongues, nectar feeding bats, tongue tip

Brown University scientists have found that a species of bat uses blood flow to reshape its tongue while feeding. The quick dynamic action makes the tongue an effective “mop” for nectar and could even inspire new industrial designs. Findings are reported in the Proceedings of the National Academy of Sciences. (more…)

Reading the Classics: It’s More than Just for Fun

By Guest PostSeptember 16, 2012Health, Scienceblood flow, brain, classic novel, cognitive complexity, critical way, english, Environment, executive function, jane austen, michigan, mri machine, natalie phillips, prejudice, pride, reading, scanner, state university, total cacophony

EAST LANSING, Mich. — Reading a classic novel such as “Pride and Prejudice” can be entertaining, but, according to new research by a Michigan State University professor, it also can provide many other benefits beyond that.

Natalie Phillips, an MSU assistant professor of English, and her team placed study participants in an MRI machine and monitored their brain flow while reading the works of Jane Austen. (more…)

UCLA Uses New Device to Replace Aortic Valve in Patients Who Can’t Have Open-Heart Surgery

By Guest PostAugust 19, 2012Healthaortic stenosis, aortic valve, blood flow, calcium deposits, cardiopulmonary bypass, chest wall, heart, heart failure, jonathan tobis, open heart surgery, quality of life, richard j shemin, ronald reagan, tavr, tavr procedure, ucla, ucla medical center, valve replacement

UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place on Aug. 9.

Ronald Reagan UCLA Medical Center is part of a growing trend of hospitals nationwide offering this new minimally invasive procedure. (more…)

UCLA Study Looks at Why Heart Attacks Cause so Much More Damage in Late Pregnancy

By Guest PostJuly 8, 2012Healthandrea iorga, blood flow, cholesterol level, diabetes, drug therapy, dysfunction, heart attack, heart disease, heart function, hua cai, ji youn youn, jingyuan li, late pregnancy, mansoureh eghbali, mitochondria, reperfusion injury, risk, risk factor, soban umar, ucla, yibin wang

Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.

While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new UCLA study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females.

The research is published in the July edition of the peer-reviewed journal Basic Research in Cardiology. (more…)

With Random Lasers, Yale Researchers Fight Random Noise, Improve Imaging

By Guest PostMay 1, 2012Sciencebeam of light, biomedical engineering, blood flow, diagnostic radiology, embryo heart, eric gershon, hui cao, illumination, imaging equipment, leds, light source, medical, michael a choma, pediatrics, photon, random laser, spatial mode, traditional lasers, yale university

Using “random lasers” as a source of illumination in medical imaging equipment could improve both processing time and the clarity of the final images, according to new research by Yale University scientists.

Imaging systems currently rely on a variety of light sources — specialty light bulbs, light-emitting diodes (LEDs), and traditional lasers. But systems using traditional lasers, the brightest of these light sources, often yield undesirable visual byproducts that mar the final picture. One common byproduct, speckle, looks something like a snowfall pattern. (more…)

University of Maryland Researcher Asks – What Does Love Look Like?

By Guest PostFebruary 11, 2012Scienceblood flow, brain area, brainwave pattern, cognition, eeg, electroencephalography, emotion, experience, fmri, functional magnetic resonance imaging, knowledge, look, love, luiz pessoa, motivated attention, Netherlands, neurocognition, p3, physiological traits, psychiatric disorder, romantic love, roses, sandra langeslag, thought

COLLEGE PARK, Md. – What does love look like? A dozen roses delivered on an ordinary weekday? Breakfast in bed? Or just a knowing glance between lovers?

While outward displays of love are fairly easy to discern, a researcher in the College of Behavioral and Social Sciences is taking a decidedly “inward” approach to documenting this most complex of human emotions. (more…)

Chemists Unlock Potential Target For Drug Development

By Guest PostJanuary 22, 2012Scienceadditives, analytical methods, bleeding, blood flow, blood platelets, bloodstream, clotting, cystic fibrosis, dana spence, diabetes, diseases, drug testing, druggable receptors, enzymes, human body, hypertension, michigan state university, molecule, nf449, p2x1, p2y receptor, pharmaceutical target, platelets, receptor, red blood cells, sickle cell anemia

EAST LANSING, Mich. — A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists.

A team led by Dana Spence of MSU’s Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1. By creating a new, simple method to study it after blood is drawn, the team has unlocked a potential new drug target for many diseases that impact red blood cells, such as diabetes, hypertension and cystic fibrosis. (more…)

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