Tag Archives: biomedical engineering

Prostate Cancer Now Detectable Using Imaging-Guided Biopsy, UCLA Study Shows

Groundbreaking research by a team of UCLA physicians and engineers demonstrates that prostate cancer — long identifiable only through painful, hit-or-miss biopsies — can be diagnosed far more easily and accurately using a new image-guided, targeted biopsy procedure.

Traditionally, prostate tumors have been found through so-called blind biopsies, in which tissue samples are taken systematically from the entire prostate in the hopes of locating a piece of tumor — a technique that dates back to the 1980s. But the cancer now appears detectable by direct sampling of tumor spots found using magnetic resonance imaging, or MRI, in combination with real-time ultrasound, the researchers say. (more…)

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Promising Nanotechnology

Nanotechnology for drug delivery shows promise in treatment of pediatric leukemia

Nanotechnology developed by Delaware scientists could potentially deliver chemotherapy to children in a way that attacks cancer cells without harming healthy cells, greatly reducing side effects.

The work, conducted by researchers in the University of Delaware’s Department of Materials Science and Engineering and Nemours Center for Childhood Cancer Research, was published this month in the journal Molecular Pharmaceutics. (more…)

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Building Molecular ‘Cages’ to Fight Disease

UCLA-created nanoscale protein containers could aid drug, vaccine delivery

UCLA biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the first step toward developing new methods of drug delivery or even designing artificial vaccines.

“This is the first decisive demonstration of an approach that can be used to combine protein molecules together to create a whole array of nanoscale materials,” said Todd Yeates, a UCLA professor of chemistry and biochemistry and a member of the UCLA–DOE Institute of Genomics and Proteomics and the California NanoSystems Institute at UCLA. (more…)

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With Random Lasers, Yale Researchers Fight Random Noise, Improve Imaging

Using “random lasers” as a source of illumination in medical imaging equipment could improve both processing time and the clarity of the final images, according to new research by Yale University scientists.

Imaging systems currently rely on a variety of light sources — specialty light bulbs, light-emitting diodes (LEDs), and traditional lasers. But systems using traditional lasers, the brightest of these light sources, often yield undesirable visual byproducts that mar the final picture. One common byproduct, speckle, looks something like a snowfall pattern. (more…)

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Microneedle Sensors May Allow Real-Time Monitoring of Body Chemistry

Researchers from North Carolina State University, Sandia National Laboratories, and the University of California, San Diego have developed new technology that uses microneedles to allow doctors to detect real-time chemical changes in the body – and to continuously do so for an extended period of time.

“We’ve loaded the hollow channels within microneedles with electrochemical sensors that can be used to detect specific molecules or pH levels,” says Dr. Roger Narayan, co-author of a paper describing the research, and a professor in the joint biomedical engineering department of NC State’s College of Engineering and the University of North Carolina at Chapel Hill. (more…)

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Hold the Phone for Vital Signs

*WPI researchers turn a smart phone into a medical monitor*

An iPhone app that measures the user’s heart rate is not only a popular feature with consumers, but it sparked an idea for a Worcester Polytechnic Institute (WPI) researcher who is now turning smart phones, and eventually tablet devices, into sophisticated medical monitors able to capture and transmit vital physiological data.

A team led by Ki Chon, professor and head of biomedical engineering at WPI, has developed a smart phone application that can measure not only heart rate, but also heart rhythm, respiration rate and blood oxygen saturation using the phone’s built-in video camera. The new app yields vital signs as accurate as standard medical monitors now in clinical use. Details of the new technology are reported in the paper “Physiological Parameter Monitoring from Optical Recordings with a Mobile Phone,” published online, in advance of print, by the journal IEEE Transactions on Biomedical Engineering. (more…)

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Brain Imaging Technique: New Hope for Understanding Parkinson’s Disease

ANN ARBOR, Mich.— A non-invasive brain imaging technique gives new hope to patients with Parkinson’s disease in finding new and better treatment plans and tracking the disease progression, a new University of Michigan study shows.

The technique uses an MRI to measure resting state brain activity oscillations, said Rachael Seidler, associate professor in the School of Kinesiology and the Department of Psychology, and study author. (more…)

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Breakthrough: Scientists Harness the Power of Electricity in the Brain

ANN ARBOR, Mich.— A paralyzed patient may someday be able to “think” a foot into flexing or a leg into moving, using technology that harnesses the power of electricity in the brain, and scientists at University of Michigan School of Kinesiology are now one big step closer.

Researchers at the school and colleagues from the Swartz Center for Computational Neuroscience at the University of California, San Diego have developed technology that for the first time allows doctors and scientists to noninvasively isolate and measure electrical brain activity in moving people. (more…)

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