Statins are safe for children living with genetically high cholesterol, according to new research from UCL, funded by the British Heart Foundation (BHF) and published in the Journal of Clinical Lipidology. (more…)
UCLA researchers have discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells — the cells that form blood vessels. The finding could point the way toward a new strategy for treating people who have suffered a heart attack, because increasing the number of blood vessels in the heart boosts its ability to heal after injury. (more…)
UCLA researchers are first to directly measure division of cardiomyocytes
Researchers from UCLA’s Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are the first to directly measure the division of heart muscle cells, proving that while such division is very rare, it does occur.
The study, conducted by assistant professor of cardiology Dr. Reza Ardehali and colleagues, resolves a recent controversy over whether the heart muscle has the power to regenerate itself. The findings are also important for future research that could lead to the regeneration of heart tissue to repair damage caused by disease or heart attack. (more…)
Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an ultrasound device that could help identify arterial plaque that is at high risk of breaking off and causing heart attack or stroke.
At issue is the plaque that builds up in arteries as we age. Some types of plaque are deemed “vulnerable,” meaning that they are more likely to detach from the artery wall and cause heart attack or stroke. (more…)
Medications used by many older people to control their blood pressure also increase the risk of serious fall injuries by 30% to 40% — injuries that have a similar effect on mortality and functional loss as the strokes and heart attacks the blood pressure drugs are meant to prevent — according to a new study by Yale School of Medicine researchers in the Feb. 24 issue of JAMA Internal Medicine.
Clinicians have long assumed that blood pressure medications are safe and effective in all older adults. That is probably true in healthy older adults, but the same might not be true in a more typical population of older adults, who commonly have several other chronic conditions, note the researchers. (more…)
Poets and physicians know that a scarred heart cannot beat the way it used to, but the science of reprogramming cells offers hope—for the physical heart, at least.
A team of University of Michigan biomedical engineers has turned cells common in scar tissue into colonies of beating heart cells. Their findings could advance the path toward regenerating tissue that’s been damaged in a heart attack. (more…)
Clinical trial evaluates treatment for patients who haven’t responded to other FDA–approved procedures
Marty Greenfield lives with crushing pain every day due to angina, a condition that is caused by an inadequate supply of blood to the heart. He has suffered a heart attack, and a coronary bypass procedure and angioplasty have provided little relief. His doctor referred him to UCLA to be considered for a heart transplant.
Dr. Jonathan Tobis, a UCLA clinical professor of cardiology, performed an angiogram and angioplasty on Greenfield, 64, but found that the patient was not a candidate for a heart transplant because his heart muscle function was still good. (more…)
Judith Lichtman, associate professor of chronic disease epidemiology at the Yale School of Public Health, discusses the risk of heart attacks for younger women. *Source: Yale University
