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How to rejuvenate ageing immune cells

By Guest PostSeptember 22, 2014Healthautophagy, bbsrc, cancer, fleischfressende wasserschlaeuchen, immunity, infections, lung cancer patients, metabolism, microfluidic chips, molecule, nutrition, recycling, rhonda jack, rishindra reddy, t cells, t lymphocytes, tumor removal surgery, vasudha murlidhar

Researchers from UCL have demonstrated how an interplay between nutrition, metabolism and immunity is involved in the process of ageing.

The two new studies, supported by the Biotechnology and Biological Sciences Research Council (BBSRC), could help to enhance our immunity to disease through dietary intervention and help make existing immune system therapies more effective. As we age our immune systems decline. Older people suffer from increased incidence and severity of both infections and cancer. In addition, vaccination becomes less efficient with age. (more…)

Blocking cells’ movement to stop the spread of cancer

By Guest PostJuly 20, 2014Healthart der taeuschung, beams of radiation, brain, heliocentrism, henry kelly, Japan, lpa, lumin wang, lungs, michael boppre, mimikry, molecule, radiation resistance, stop, truth about galileo, wespenmimikry

Insights into how cells move through the body could lead to innovative techniques to stop cancer cells from spreading and causing secondary tumours, according to new UCL research.

Scientists discovered that cells can change into an invasive, liquid-like state to readily navigate the narrow channels in our body. This transformation is triggered by chemical signals, which could be blocked in order to stop cancer cells from spreading. (more…)

SOFS Take to Water

By Guest PostJanuary 5, 2014Science2d honeycomb, aka chemistry, berkeley lab, chemical signals, DNA, double helix, emergence of nanotechnology, force, metal organic frameworks, mofs, molecule, non covalent bonds, saxs, sofs, solubility in water, supramolecular chemistry, supramolecular organic frameworks, van der waals, xin zhao, yi liu, zhan ting li

Researchers at Berkeley Lab’s Molecular Foundry Create First Soluble 2D Supramolecular Organic Frameworks

Supramolecular chemistry, aka chemistry beyond the molecule, in which molecules and molecular complexes are held together by non-covalent bonds, is just beginning to come into its own with the emergence of nanotechnology. Metal-organic frameworks (MOFs) are commanding much of the attention because of their appetite for greenhouse gases, but a new player has joined the field – supramolecular organic frameworks (SOFs). Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have unveiled the first two-dimensional SOFs that self-assemble in solution, an important breakthrough that holds implications for sensing and separation technologies, energy sciences, and, perhaps most importantly, biomimetics. (more…)

Taking a New Look at Carbon Nanotubes

By Guest PostDecember 7, 2013Scienceactin filaments, advancing nanotube technology, anisotropic, berkeley lab, carbon nanotubes, crystal, Environment, feng wang, functional device, fused silica substrate, graphene nanoribbons, human hair, kaihui liu, molecule, na, nanobiomaterials, nanorods, numerical aperture, optical anisotropy, plethora, polarization, semiconductor nanowires, species, substrates, xiaoping hong

Berkeley Researchers Develop Technique For Imaging Individual Carbon Nanotubes

Despite their almost incomprehensibly small size – a diameter about one ten-thousandth the thickness of a human hair – single-walled carbon nanotubes come in a plethora of different “species,” each with its own structure and unique combination of electronic and optical properties. Characterizing the structure and properties of an individual carbon nanotube has involved a lot of guesswork – until now.

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have developed a technique that can be used to identify the structure of an individual carbon nanotube and characterize its electronic and optical properties in a functional device. (more…)

MU Research Sheds Light on Nerve Regeneration Following Spinal Cord Injury

By Guest PostDecember 6, 2013Healthactivation, andrew mcclellan, chemical signals, cyclic amp, eel like fish, emily frisch, group of molecules, level of injury, locomotion, mammals, molecule, nerve cell, nerve regeneration, neurons, reticulospinal neurons, sea lamprey, second messengers, spinal cord injury, timothy pale, university of missouri, vertebrate

COLUMBIA, Mo. – Fish, unlike humans, can regenerate nerve connections and recover normal mobility following an injury to their spinal cord. Now, University of Missouri researchers have discovered how the sea lamprey, an eel-like fish, regrows the neurons that comprise the long nerve “highways” that link the brain to the spinal cord. Findings may guide future efforts to promote recovery in humans who have suffered spinal cord injuries.

“There is a lot of attention to why, following a spinal cord injury, neurons regenerate in lower vertebrates, such as the sea lamprey, and why they don’t in higher vertebrates, such as humans,” said Andrew McClellan, professor of biological sciences in the College of Arts and Science and director of the UM Spinal Cord Injury Research Program (SCIRP). (more…)

Flawed Diamonds: Gems for New Technology

By Guest PostOctober 4, 2013Scienceatom, carbon atom, crystal structure, data storage, Diamond, diamonds, dmitry budker, edward muybridge, electronic properties, femtoseconds, flawed diamonds, galloping horses, gems, graham fleming, molecule, nanosecond, new technology, nitrogen vacancy center, optical, quantum computing, three dimensional lattice, ua, ultrafast spectroscopy, university of arizona, vanessa huxter, vibrational mode

Using ultra-fast laser pulses, a team of researchers led by UA assistant professor Vanessa Huxter has made the first detailed observation of how energy travels through diamonds containing nitrogen-vacancy centers – promising candidates for a variety of technological advances such as quantum computing.

A team of researchers led by University of Arizona assistant professor Vanessa Huxter has made the first detailed observation of how energy travels through diamonds that contain nitrogen-vacancy centers – defects in which two adjacent carbon atoms in the diamond’s crystal structure are replaced by a single nitrogen atom and an empty gap. (more…)

Green Tea Extract Interferes with the Formation of Amyloid Plaques in Alzheimer’s Disease

By Guest PostMarch 15, 2013Healthakiko kochi, alaina detoma, alzheimer's disease, ayyalusamy ramamoorthy, benefit, bing ye, brain, brandon ruotoloa, copper, egcg, epigallocatechin 3 gallate, green tea, iron, jung suk choi, life sciences institute, metal associated amyloids, mi hee lim, molecule, neurodegenerative conditions, powerful antioxidants, sanghyun lee, specific proteins, structure centric, subramanian vivekanandan, suk joon hyung, tweak, university of michigan, zinc

ANN ARBOR — Researchers at the University of Michigan have found a new potential benefit of a molecule in green tea: preventing the misfolding of specific proteins in the brain.

The aggregation of these proteins, called metal-associated amyloids, is associated with Alzheimer’s disease and other neurodegenerative conditions. (more…)

How Computers Push on the Molecules They Simulate

By Guest PostJanuary 9, 2013Scienceacceleration, albert einstein, algorithm, analytical results, artifacts, atoms and molecules, behavior, Berkeley, berkeley lab, calculation, california, california institute, chemical fuel, collide, computer method, conserve energy, david sivak, digital representation, digitize time, dna repair, driving force, effective friction, energy dense, equation, error, finite time steps, fluid, french physicist, gavin crooks, john chodera, langevin dynamics, model brownian motion, modeling molecular system, modern computer, molecular machines, molecular scale motion, molecule, momentum, natural system, nonequilibrium driving force, nonequilibrium statistical mechanics, particle, passage of time, paul langevin, photosynthesis, pollen grain, qb3, quantitative biosciences, quantum mechanics, real world, simulation, source, tenacious errors, theoretical method, thermal energy, toy models, university, velocity, water, water molecules

Berkeley Lab bioscientists and their colleagues decipher a far-reaching problem in computer simulations

Because modern computers have to depict the real world with digital representations of numbers instead of physical analogues, to simulate the continuous passage of time they have to digitize time into small slices. This kind of simulation is essential in disciplines from medical and biological research, to new materials, to fundamental considerations of quantum mechanics, and the fact that it inevitably introduces errors is an ongoing problem for scientists.

Scientists at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have now identified and characterized the source of tenacious errors and come up with a way to separate the realistic aspects of a simulation from the artifacts of the computer method. The research was done by David Sivak and his advisor Gavin Crooks in Berkeley Lab’s Physical Biosciences Division and John Chodera, a colleague at the California Institute of Quantitative Biosciences (QB3) at the University of California at Berkeley. The three report their results in Physical Review X. (more…)

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