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UCLA Study Looks at Why Heart Attacks Cause so Much More Damage in Late Pregnancy

By Guest PostJuly 8, 2012Healthandrea iorga, blood flow, cholesterol level, diabetes, drug therapy, dysfunction, heart attack, heart disease, heart function, hua cai, ji youn youn, jingyuan li, late pregnancy, mansoureh eghbali, mitochondria, reperfusion injury, risk, risk factor, soban umar, ucla, yibin wang

Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.

While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new UCLA study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females.

The research is published in the July edition of the peer-reviewed journal Basic Research in Cardiology. (more…)

Biosensor Illuminates Compounds to Aid Fight Against TB

By Guest PostMay 16, 2012Scienceagbioresearc, antibiotics, biosensor, chris wilson, chronic infection, chronic tb, drug resistant, drug therapy, environmental oxygen, global health, glows green, grand challenges explorations, immunization, infection, nutrition, oxygen sensing system, robert abramovitch, synthetic biosensor, tb, tb bacterium, treatment, tuberculosis, tuberculosis epidemic

EAST LANSING, Mich. — For his work on developing new treatments for tuberculosis, a Michigan State University researcher has been named a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

Robert Abramovitch of MSU’s Department of Microbiology and Molecular Genetics is using a synthetic biosensor that glows green in response to conditions that mimic human tuberculosis infection. He will screen for compounds that target chronic TB infection and may help shorten therapy or treat multidrug-resistant TB, which does not respond well to existing antibiotics. (more…)

Heat Therapy Could Be New Treatment for Parasitic Skin Disease

By Guest PostFebruary 20, 2011Healthabhay satoskar, antibiotic skin cream, antimonials, complex drug regimen, compromised immune system, cutaneous leishmaniasis, drug therapy, heat therapy, hiv infection, immune compromised people, immune systems, leishmania parasites, middle east, neha prasad, oral anti-inflammatory, parasitic disease, parasitic skin infection, radio-frequency-induced heat, sand flies, skin infection, skin lesions, sodium stibogluconate, tropical and subtropical regions

COLUMBUS, Ohio – Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world.

The researchers successfully treated the skin infection with heat therapy in two patients whose immune systems were deficient, which lowered their bodies’ ability to respond to medication. Both patients have remained free of the parasitic disease, called cutaneous leishmaniasis, for more than a year since receiving the heat treatment.

That long-term effectiveness, especially in people with compromised immune systems, makes this one-time application of heat to skin lesions an appealing alternative to the conventional treatment for the infection — a series of about 20 consecutive daily drug injections that is rife with compliance problems, researchers say. (more…)

Tag Archives: drug therapy

UCLA Study Looks at Why Heart Attacks Cause so Much More Damage in Late Pregnancy

Biosensor Illuminates Compounds to Aid Fight Against TB

Heat Therapy Could Be New Treatment for Parasitic Skin Disease