age related – Shamskm: A site to exchange knowledge and solutions

Major cause of blindness linked to calcium deposits in the eye

Microscopic spheres of calcium phosphate have been linked to the development of age-related macular degeneration (AMD), a major cause of blindness, by UCL-led research.

AMD affects 1 in 5 people over 75, causing their vision to slowly deteriorate, but the cause of the most common form of the disease remains a mystery.* The ability to spot the disease early and reliably halt its progression would improve the lives of millions, but this is simply not possible with current knowledge and techniques. (more…)

UCLA Findings Buck Conventional Wisdom about How Stress-Response Protein Works

By Guest PostFebruary 11, 2013Health, Scienceage related, biomarker, cell stress, cell types, chaperones, class of molecules, clouding, conventional wisdom, environmental conditions, epithelial cells, eye institute, eye lens, fibroblast cells, gene, heart muscle degeneration, heat shock factor, heat shock factor4, heat shock protein, hsf1, hsf4, infection, inflammation, jules stein, macular degeneration, monitor for diseases, multiple sclerosis, stress response protein, toxins, transcription factors, ucla researchers, zhe jing, αb crystallin

UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a stress-response protein in all cells that come under stress instead expresses the protein only in specific cell types.

The research team, from the Jules Stein Eye Institute at UCLA and the UCLA Division of Pulmonary and Critical Care Medicine, focused on αB-Crystallin, one of a class of molecules known as heat shock proteins, which are involved in the folding and unfolding of other proteins, helping them recover from stress so they can do their job. (more…)

Tag Archives: age related

Major cause of blindness linked to calcium deposits in the eye

UCLA Findings Buck Conventional Wisdom about How Stress-Response Protein Works