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UCLA Findings Buck Conventional Wisdom about How Stress-Response Protein Works

By Guest PostFebruary 11, 2013Health, Scienceage related, biomarker, cell stress, cell types, chaperones, class of molecules, clouding, conventional wisdom, environmental conditions, epithelial cells, eye institute, eye lens, fibroblast cells, gene, heart muscle degeneration, heat shock factor, heat shock factor4, heat shock protein, hsf1, hsf4, infection, inflammation, jules stein, macular degeneration, monitor for diseases, multiple sclerosis, stress response protein, toxins, transcription factors, ucla researchers, zhe jing, αb crystallin

UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a stress-response protein in all cells that come under stress instead expresses the protein only in specific cell types.

The research team, from the Jules Stein Eye Institute at UCLA and the UCLA Division of Pulmonary and Critical Care Medicine, focused on αB-Crystallin, one of a class of molecules known as heat shock proteins, which are involved in the folding and unfolding of other proteins, helping them recover from stress so they can do their job. (more…)

How Tattoos ‘Move’ With Age

The dyes which are injected into the skin to create tattoos move with time – permanently altering the look of a given design. In this month’s Mathematics Today Dr Ian Eames, a Reader in Fluid Mechanics at UCL, publishes a mathematical model enabling us to estimate the movement of these ink particles and predict how specific tattoo designs will look several years in the future.

“Tattoos are incredibly popular worldwide with more than a third of 18-25 year olds in the USA sporting at least one design,” says Dr Eames. “A great deal of work has already been done on the short term fate of ink particles in the skin, tracking them over periods of just a few months – but much less is known about how these particles move over longer periods of time. (more…)

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UCLA Findings Buck Conventional Wisdom about How Stress-Response Protein Works

How Tattoos ‘Move’ With Age