infection – Page 3 – Shamskm: A site to exchange knowledge and solutions

Behind Closed Doors

By Guest PostAugust 28, 2012Scienceabscisic acid, amutha sampath kumar, arabidopsis thaliana, bacillus subtilis, beneficial, bug, carbon dioxide, deborah powell, delphis f levia, disease, foliar pathogen, harsh bais, infection, jeffrey l caplan, kirk j czymmek, leaf pore, microscopic pore, mineral, oxygen, pathogen, plant immunity, pseudomonas syringae, pstdc3000, rhizobacteria, roots signal, salicylic acid, soil bacteria, stomata, tomato dc3000, university of delaware, venkatachalam lakshmanan, water

UD researchers show how beneficial soil bacteria can boost plant immunity

With the help of beneficial bacteria, plants can slam the door when disease pathogens come knocking, University of Delaware researchers have discovered.

A scientific team under the leadership of Harsh Bais, assistant professor of plant and soil sciences in UD’s College of Agriculture and Natural Resources, found that when pathogens attempt to invade a plant through the tiny open pores in its leaves, a surprising ally comes to the rescue. Soil bacteria at the plant’s roots signal the leaf pores to close, thwarting infection. (more…)

Common Parasite May Trigger Suicide Attempts

By Guest PostAugust 18, 2012Health, Scienceamerica, biological change, biological mechanism, brain, brain cell, damage, depression, harmless, infection, inflammation, lena brundin, parasite, parkinsons disease, suicide attempt, symptom, t gondii, teodor postolache, toxoplasma gondii, united states

EAST LANSING, Mich. — A parasite thought to be harmless and found in many people may actually be causing subtle changes in the brain, leading to suicide attempts.

New research appearing in the August issue of The Journal of Clinical Psychiatry adds to the growing work linking an infection caused by the Toxoplasma gondii parasite to suicide attempts. Michigan State University’s Lena Brundin was one of the lead researchers on the team.

About 10-20 percent of people in the United States have Toxoplasma gondii, or T. gondii, in their bodies, but in most it was thought to lie dormant, said Brundin, an associate professor of experimental psychiatry in MSU’s College of Human Medicine. In fact, it appears the parasite can cause inflammation over time, which produces harmful metabolites that can damage brain cells. (more…)

Meditation Reduces Loneliness

By Guest PostAugust 15, 2012Health, Sciencealzheimer's disease, brain, chronic inflammation, crp, david creswell, depression, expression, heart disease, helen lavretsky, immune system, infection, inflammation, inflammatory gene, loneliness, mbsr, meditation, meditative technique, michael irwin, mindfulness, natural component, nf kb, pro inflammatory gene, protein marker, risk, tai chi, yoga

UCLA study also finds that mindfulness technique benefits immune system

Many elderly people spend their last years alone. Spouses pass and children scatter. But being lonely is much more than a silent house and a lack of companionship. Over time, loneliness not only takes a toll on the psyche but can have a serious physical impact as well.

Feeling lonely has been linked to an increased risk of heart disease, Alzheimer’s disease, depression and even premature death. Developing effective treatments to reduce loneliness in older adults is essential, but previous treatment efforts have had limited success. (more…)

Biosensor Illuminates Compounds to Aid Fight Against TB

By Guest PostMay 16, 2012Scienceagbioresearc, antibiotics, biosensor, chris wilson, chronic infection, chronic tb, drug resistant, drug therapy, environmental oxygen, global health, glows green, grand challenges explorations, immunization, infection, nutrition, oxygen sensing system, robert abramovitch, synthetic biosensor, tb, tb bacterium, treatment, tuberculosis, tuberculosis epidemic

EAST LANSING, Mich. — For his work on developing new treatments for tuberculosis, a Michigan State University researcher has been named a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

Robert Abramovitch of MSU’s Department of Microbiology and Molecular Genetics is using a synthetic biosensor that glows green in response to conditions that mimic human tuberculosis infection. He will screen for compounds that target chronic TB infection and may help shorten therapy or treat multidrug-resistant TB, which does not respond well to existing antibiotics. (more…)

When Cells Hit the Wall: UCLA Engineers Put The Squeeze on Cells to Diagnose Disease

By Guest PostMay 6, 2012Health, Scienceaids, amander clark, balloon, cancer, cells, chemical tags, chronic inflammation, cytopathologist, daniel gossett, deformability cytometer, diagnose disease, dino di carlo, dna arrangement, elastic properties, extract information, henry tse, honey, immune disorder, immune system, infection, jian yu rao, mesothelial cells, microfluidic chip, nuclei, rubber balloon, shape, software, steven chu, Technology, ucla engineers, viscous, white blood cells

If you throw a rubber balloon filled with water against a wall, it will spread out and deform on impact, while the same balloon filled with honey, which is more viscous, will deform much less. If the balloon’s elastic rubber was stiffer, an even smaller change in shape would be observed.

By simply analyzing how much a balloon changes shape upon hitting a wall, you can uncover information about its physical properties.

Although cells are not simple sacks of fluid, they also contain viscous and elastic properties related to the membranes that surround them; their internal structural elements, such as organelles; and the packed DNA arrangement in their nuclei. Because variations in these properties can provide information about cells’ state of activity and can be indicative of diseases such as cancer, they are important to measure. (more…)

Rebuilding a Heart, Saving a Life

By Guest PostApril 19, 2012Healthamerican patient, angela irizarry, birthday, blood vessel, blue babies, bone marrow, bridgeport, cardiac surgeon, christopher breuer, circulatory system, claudia irizarry, congenital heart defect, connecticut, fda, function, gary kopf, hypoplastic, infection, inflammatory response, left heart syndrome, mark saltzman, natural cell, operation, organ, oxygenated blood, polymer, synthetic grafts, synthetic nature, tissue engineered, toshi shinoka, united states, yale doctor, young girl

A young girl in Bridgeport, Connecticut, born with one of the most serious, life-threatening congenital heart defects known, is on her way to living a normal life thanks to Yale doctors who developed and performed the first operation of its kind in the United States.

Angela Irizarry was the first American patient to receive a tissue-engineered blood vessel made of her own natural cells. (more…)

Pigeons’ Homing Skill Not Down to Iron-Rich Beak Cells

By Guest PostApril 16, 2012Natureballs of iron, beaks, david keays, electrical signal, Environment, imaging technique, infection, iron, macrophages, magnetic cell, magnetic field, magnetic nerve cell, mark lythgoe, mechanism, migratory bird, navigation, nerve cell, pigeon, red blood cell, state-of-the-art, theory, university college london, vienna, white blood cell

The theory that pigeons’ famous skill at navigation is down to iron-rich nerve cells in their beaks has been disproved by a new study published in Nature.

The study shows that iron-rich cells in the pigeon beak are in fact specialised white blood cells, called macrophages. This finding, which shatters the established dogma, puts the field back on course as the search for magnetic cells continues. (more…)

Scientists Identify Novel Pathway for T Cell Activation in Leprosy

By Guest PostApril 2, 2012Sciencecell signaling molecule, delphine j lee, dendritic cells, immune cells, infection, interleukin 32, lepromatous leprosy, leprosy, leprosy pathogen, mirjam schenk, monocytes, mycobacteria, mycobacterium leprae, nod2, peter a sieling, protein, robert modlin, skin, stephan r krutzik, t cells, tlr2, tuberloid leprosy, white blood cell

*Findings may help lead to new treatments for infectious diseases, cancer*

UCLA researchers have pinpointed a new mechanism that potently activates T cells, the group of white blood cells that plays a major role in fighting infections.

The team specifically studied how dendritic cells, immune cells located at the site of an infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae. Dendritic cells, like scouts in the field of a military operation, deliver key information about an invading pathogen that helps activate the T cells in launching a more effective attack. (more…)

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