Tag Archives: immune cells

Starved T cells allow hepatitis B to silently infect liver

Hepatitis B stimulates processes that deprive the body’s immune cells of key nutrients that they need to function, finds new UCL-led research funded by the Medical Research Council and Wellcome Trust.

The work helps to explain why the immune system cannot control hepatitis B virus infection once it becomes established in the liver, and offers a target for potential curative treatments down the line. The research also offers insights into controlling the immune system, which could be useful for organ transplantation and treating auto-immune diseases. (more…)

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Scientists Identify Novel Pathway for T Cell Activation in Leprosy

*Findings may help lead to new treatments for infectious diseases, cancer*

UCLA researchers have pinpointed a new mechanism that potently activates T cells, the group of white blood cells that plays a major role in fighting infections.

The team specifically studied how dendritic cells, immune cells located at the site of an infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae. Dendritic cells, like scouts in the field of a military operation, deliver key information about an invading pathogen that helps activate the T cells in launching a more effective attack. (more…)

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Scientists Pinpoint How Vitamin D May Help Clear Amyloid Plaques Found in Alzheimer’s

A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.

Published in the March 6 issue of the Journal of Alzheimer’s Disease, the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein. (more…)

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