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Starved T cells allow hepatitis B to silently infect liver

Hepatitis B stimulates processes that deprive the body’s immune cells of key nutrients that they need to function, finds new UCL-led research funded by the Medical Research Council and Wellcome Trust.

The work helps to explain why the immune system cannot control hepatitis B virus infection once it becomes established in the liver, and offers a target for potential curative treatments down the line. The research also offers insights into controlling the immune system, which could be useful for organ transplantation and treating auto-immune diseases. (more…)

Research Shows Why One Bacterial Infection is So Deadly in Cystic Fibrosis

By Guest PostApril 28, 2012Scienceacute infection, amal amer, antibiotics, anwari akhter, arwa abu khweek, autophagy, bacterial infection, bacterium, basant abdulrahman, benjamin kopp, burkholderia cenocepacia, cf, chronic destruction, cystic fibrosis, genetic mutation, kyle caution, lung infection, lung tissue, macrophage, mia tazi, mice and humans, molecule, ohio state university, p62, rapamycin

COLUMBUS, Ohio – Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.

The bacterium, Burkholderia cenocepacia, causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Cystic fibrosis is a chronic disorder characterized by a buildup of mucus in the lungs and other parts of the body, and various types of lung infection are responsible for about 85 percent of deaths in these patients. (more…)

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Starved T cells allow hepatitis B to silently infect liver

Research Shows Why One Bacterial Infection is So Deadly in Cystic Fibrosis