mice and humans – Shamskm: A site to exchange knowledge and solutions

Research Shows Why One Bacterial Infection is So Deadly in Cystic Fibrosis

By Guest PostApril 28, 2012Scienceacute infection, amal amer, antibiotics, anwari akhter, arwa abu khweek, autophagy, bacterial infection, bacterium, basant abdulrahman, benjamin kopp, burkholderia cenocepacia, cf, chronic destruction, cystic fibrosis, genetic mutation, kyle caution, lung infection, lung tissue, macrophage, mia tazi, mice and humans, molecule, ohio state university, p62, rapamycin

COLUMBUS, Ohio – Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.

The bacterium, Burkholderia cenocepacia, causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Cystic fibrosis is a chronic disorder characterized by a buildup of mucus in the lungs and other parts of the body, and various types of lung infection are responsible for about 85 percent of deaths in these patients. (more…)

Of Mice and Men

By Guest PostSeptember 18, 2011Sciencebret payseur, chromosomes, diseases, DNA, dna sequences, evolution of disease, evolutionary relationships, genetic codes, genomes, genomic information, identification of genes, madison, mice and humans, michael white, mouse strains, national science foundation, strains of common lab mice, university of wisconsin

*The genomes of 17 common strains of lab mice were sequenced to advance genetic studies of human diseases*

Scientists have sequenced the genomes (genetic codes) of 17 strains of common lab mice–an achievement that lays the groundwork for the identification of genes responsible for important traits, including diseases that afflict both mice and humans.

Mice represent the premier genetic model system for studying human diseases. What’s more, the 17 strains of mice included in this study are the most common strains used in lab studies of human diseases. By enabling scientists to list all DNA differences between the 17 strains, the new genome sequences will speed the identification of subsets of mutations and genes that contribute to disease. (more…)

Tag Archives: mice and humans

Research Shows Why One Bacterial Infection is So Deadly in Cystic Fibrosis

Of Mice and Men