As debate increases about whether female lacrosse players should wear headgear, a new study reports measurements of the accelerations that stick blows deliver to the head. The study also measured the dampening effect of various kinds of headgear.
PROVIDENCE, R.I. [Brown University] — Lacrosse players swing hard, which is why errant stick blows are the leading cause of concussion in girls’ and women’s lacrosse. In a new study, researchers measured how much the worst blows accelerate the head and how much different kinds of headgear could reduce those accelerations. (more…)
Since 1994 cancer doctors affiliated with the Alpert Medical School have had a place with funding, administrative, and collegial support to develop and test novel cancer treatments: The Brown University Oncology Research Group.
PROVIDENCE, R.I. [Brown University] — Too few cancer patients, especially those with pancreatic cancer, get to the point that Raymond Sabella reached in the spring of 2014. Ten months after he began his trek from the diagnosis of an inoperable tumor to experimental chemotherapy and then radiation, he reports feeling great. He’s gaining back some of the weight he lost, but not too much, and something else is back, too. (more…)
In a new discovery reported in the Journal of Biological Chemistry, Brown University and Lifespan researchers show that in the brain cells of rats, obesity impedes the production of a hormone that curbs appetite and inspires calorie burning. The root cause appears to be a breakdown in the protein-processing mechanism of the cells. In the lab, the researchers showed they could fix the breakdown with drugs.
PROVIDENCE, R.I. [Brown University] — With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress appetite and to increase calorie burning. (more…)
U.S. emergency care costs may be more than twice previously published estimates, according to a new analysis that critiques those estimates, argues for improved accounting, and suggests considering the value of emergency care as well as total spending.
PROVIDENCE, R.I. [Brown University] — Alternately praised in the aftermath of horrible tragedies as a heroic service and lamented in policy debates as an expensive safety net for people without primary care, emergency medicine is often a hot topic. Despite that importance, an analysis published online April 26 in the Annals of Emergency Medicine finds that national expenditures on emergency care are likely significantly higher than previously thought.
“The ER has become increasingly important as a place where people go for acute unscheduled care, however there has been little rigorous analysis of its cost structure,” said paper lead author Dr. Michael Lee, assistant professor of emergency medicine in the Warren Alpert Medical School of Brown University and a physician at Rhode Island Hospital and The Miriam Hospital. (more…)
Dedicated, passionate and energetic, M.D./Ph.D. student Angel Byrd has earned many accolades and research opportunities. But she only recently won a young scientist’s most coveted prize: publication as lead author of a paper highly esteemed by her colleagues.
Well on her way to fulfilling her dreams both in research and medicine, Brown University M.D./Ph.D. student Angel Byrd nevertheless had recently begun to define herself by what was missing, said her adviser, Dr. Jonathan Reichner, associate professor of surgery (research) at Rhode Island Hospital. She still wasn’t a published author.
For years she had dedicated herself to studying how immune system cells capture invading fungal pathogens. Like those cells, called neutrophils, she had seized on seemingly every opportunity that had come her way. (more…)
On a long spaceflight unique conditions including microgravity could give microbes the upper hand, but not if astronauts and their spacecrafts are properly prepared. In a new paper, infectious disease expert Dr. Leonard Mermel brings together a broad base of research to come up with specific recommendations for keeping astronauts safe in deep space.
PROVIDENCE, R.I. [Brown University] — The cabin of a spacecraft halfway to Mars would be the least convenient place — one cannot say “on earth” — for a Salmonella or Pneumococcus outbreak, but a wide-ranging new paper suggests that microgravity and prolonged space flight could give unique advantages to germs. What’s a space agency to do? Brown University and Rhode Island Hospital infectious disease expert Dr. Leonard Mermel offers several ideas.
And no, they are not to add more Vitamin C to the Tang, or to give each crew member a bottle of Purell. It’s a lot more complicated than that. (more…)
