Tag Archives: catheters

Brown University Oncology Research Group: Twenty years of cancer treatment trials

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Since 1994 cancer doctors affiliated with the Alpert Medical School have had a place with funding, administrative, and collegial support to develop and test novel cancer treatments: The Brown University Oncology Research Group.

PROVIDENCE, R.I. [Brown University] — Too few cancer patients, especially those with pancreatic cancer, get to the point that Raymond Sabella reached in the spring of 2014. Ten months after he began his trek from the diagnosis of an inoperable tumor to experimental chemotherapy and then radiation, he reports feeling great. He’s gaining back some of the weight he lost, but not too much, and something else is back, too. (more…)

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Selenium Controls Staph on Implant Material

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A coating of selenium nanoparticles significantly reduces the growth of Staphylococcus aureus on polycarbonate, a material common in implanted devices such as catheters and endotracheal tubes, engineers at Brown University report in a new study.

PROVIDENCE, R.I. [Brown University] — Selenium is an inexpensive element that naturally belongs in the body. It is also known to combat bacteria. Still, it had not been tried as an antibiotic coating on a medical device material. In a new study, Brown University engineers report that when they used selenium nanoparticles to coat polycarbonate, the material of catheters and endotracheal tubes, the results were significant reductions in cultured populations of Staphylococcus aureus bacteria, sometimes by as much as 90 percent.

“We want to keep the bacteria from generating a biofilm,” said Thomas Webster, professor of engineering and orthopaedics, who studies how nanotechnology can improve medical implants. He is the senior author of the paper, published online this week in the Journal of Biomedical Materials Research A. (more…)

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