Tag Archives: leukemia

Scientists Find Leukemia’s Surroundings Key to its Growth

AUSTIN, Texas — Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous. The finding, published in the Proceedings of the National Academy of Sciences, contributes to a growing body of research that implicates the environment around a cancer in its spread — an area of study that holds promise for new alternatives to treat the disease. (more…)

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UCLA Scientists Discover ‘Missing Link’ Between Blood Stem Cells, Immune System

UCLA researchers have discovered a type of cell that is the “missing link” between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy immune system is produced and how disease can lead to poor immune function.

The research was done using human bone marrow, which contains all the stem cells that produce blood during post-natal life. (more…)

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How Megakaryocytes Get so Big — and The Bad Things That Happen When They Don’t

Yale researchers have discovered how megakaryocytes — giant blood cells that produce wound-healing platelets — manage to grow 10 to 15 times larger than other blood cells.

The findings, to be published March 13 in the journal Developmental Cell, also hint at how a malfunction in this process may cause a form of leukemia. (more…)

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Research Shows a Promising New Method to Reduce Graft-Versus-Host-Disease After Bone Marrow Transplantation

ANN ARBOR, Mich.—University of Michigan researchers have discovered a new method to prevent the immune-system attacks that often occur following bone marrow transplants.

Bone marrow transplantation can cure patients with leukemia and other cancers even when the disease is resistant to other treatments. The success of this procedure relies on killing cancer cells by using immune cells from a bone marrow donor while avoiding an immune attack against the patient’s organs, which causes a dangerous complication called graft-versus-host disease. (more…)

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