Author Archives: Guest Post

comScore Releases Report, “Next-Generation Strategies for Advertising to Millennials”

By Guest PostJanuary 24, 2012Technologyarf webinar, bert miklosi, Comscore, digital, internet, millennial generation, Technology, tv, types of advertising, validated drivers

*Study Looks at Unique Characteristics of America’s Younger Consumers and Their Responses to Advertising across Platforms*

RESTON, VA, January 24, 2012 – comScore, Inc., a leader in measuring the digital world, today released the report Next-Generation Strategies for Advertising to Millennials, highlighting the results from a recent comScore study that identifies the unique characteristics of the Millennial generation, commonly defined as persons born between 1981 and 2000. The study examined Millennials’ responses to different types of advertising, including TV and digital, compared to older generations, and how marketers can most effectively target this large and important segment. To download a complimentary copy of the report, please visit: https://www.comscore.com/Millennials. The study results will also be presented via a live webinar through the Advertising Research Foundation on January 31st. (more…)

Vision Improves Modestly in Patients after Human Embryonic Stem Cells Transplants

By Guest PostJanuary 24, 2012Health, Scienceblind patients, central visual rescue, clinical trials, Europe, eye diseases, eyes, human embryonic stem cells, immunosuppression therapy, lancet, macular degeneration, photoreceptor, retinal cells, retinal pigment epithelial, rpe, stargardts macular dystrophy, stem cells, steven schwartz, therapeutic use, transplantation, united states, vision

Researchers at UCLA’s Jules Stein Eye Institute and colleagues who successfully transplanted specialized retinal cells derived from human embryonic stem cells into the eyes of two legally blind patients report that the transplants appear safe and that both patients have experienced modest improvement in their vision.

The preliminary findings, published online Jan. 23 in the journal The Lancet, represent a milestone in the therapeutic use of stem cells and may pave the way for a new therapy to treat eye diseases, the researchers said. Because this is the first time physicians have applied the power of regenerative medicine to eye disease, the clinical trials are being watched closely by scientists, stem-cell therapy advocates and the public. (more…)

New U-M Computer Model Predicts Cholera Outbreaks Up To 11 Months in Advance

By Guest PostJanuary 23, 2012Environment, Scienceaaron king, annual monsoon flooding, attack rates, bacterium, Bangladesh, capital city, cholera cases, cholera outbreaks, climate change, climate factors, climate sensitive urban core, climate variability, computer model, cycles of cholera, dhaka, diarrheal disease, disease transmission, ecology, el niño southern oscillation, enso episode, fecal oral diseases, mercedes pascual, michael emch, mohammad yunus, pathogen, post monsoon, prediction, risk factors, robert reiner, sanitary conditions, space and time, spatial location, university of michigan, urban periphery, vaccination, vibrio cholera, warning system

ANN ARBOR, Mich.— A new University of Michigan computer model of disease transmission in space and time can predict cholera outbreaks in Bangladesh up to 11 months in advance, providing an early warning system that could help public health officials there.

The new forecast model applies specifically to the capital city of Dhaka and incorporates data on both year-to-year climate variability and the spatial location of cholera cases at the district level. This allowed the researchers to study both local variation in disease transmission and response to climate factors within the megacity of 14 million people. (more…)

Gene Research Sheds Light on Timing of Menopause

By Guest PostJanuary 23, 2012Healthanna murray, breast cancer, cardiovascular disease, damage, early menopause, genes, genetic studies, genome, heart disease, hormonal change, hormonal regulation, immune system, joanne murabito, john perry, kathryn lunetta, menopause, menopause onset, oestrogen exposure, post menopausal women, pre menopausal, repair, reproductive disorders, reproductive lifespan, timing of menopause, university of exeter, university of oxford

An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause.

These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease.

Menopause is a major hormonal change that affects most women when they are in their early 50s. The timing of menopause can have a huge impact on fertility, as well as influencing the risk of a range of common diseases such as breast cancer. It has been known for some time that genetic factors influenced the onset of menopause, however until recently very few genes had been identified.

In the new study, published in the journal Nature Genetics on 22 January 2012, Dr Anna Murray, University of Exeter, Peninsula College of Medicine and Dentistry (PCMD) Dr John Perry, PCMD and WTCHG, University of Oxford, and dozens of international collaborators, examined the genomes of over 50,000 women. They identified 13 novel gene regions associated with menopause onset, and confirmed four previously identified. Most of the 17 regions include genes related to DNA damage/repair or the immune system, whilst others are linked to hormonal regulation. (more…)

Mysterious Flotsam in Gulf of Mexico Came from Deepwater Horizon Rig, Study Finds

By Guest PostJanuary 23, 2012Environmentbuoyancy, catherine carmichael, chandeleur islands, chemical forensics, chris reddy, coast guard, coastal beaches, coastal pollution impacts, cuming corporation, dauphin island, dauphin island sea lab, deepwater horizon disaster, elmers beach, floating oil, flotsam, future oil spills, grand isle, gulf of mexico, halo of oil sheen, honeycomb material, louisiana, macondo well, merv fingas, noaa, oceanographer, offshore oil spills, oil and gas industry, sargassum weed, satellites, seafloor, spill site, syntactic foam, waves, whoi, william graham, wind, woods hole oceanographic institution

*Tracking Debris from Damaged Oil Rigs Could Help Forecast Coastal Impacts in the Future*

Shortly after the Deepwater Horizon disaster, mysterious honeycomb material was found floating in the Gulf of Mexico and along coastal beaches. Using state-of-the-art chemical forensics and a bit of old-fashioned detective work, a research team led by scientists at Woods Hole Oceanographic Institution (WHOI) confirmed that the flotsam were pieces of material used to maintain buoyancy of the pipe bringing up oil from the seafloor.

The researchers also affirmed that tracking debris from damaged offshore oil rigs could help forecast coastal pollution impacts in future oil spills and guide emergency response efforts—much the way the Coast Guard has studied the speed and direction of various floating debris to guide search and rescue missions. The findings were published Jan. 19 in Environmental Research Letters. (more…)

Chemists Unlock Potential Target For Drug Development

By Guest PostJanuary 22, 2012Scienceadditives, analytical methods, bleeding, blood flow, blood platelets, bloodstream, clotting, cystic fibrosis, dana spence, diabetes, diseases, drug testing, druggable receptors, enzymes, human body, hypertension, michigan state university, molecule, nf449, p2x1, p2y receptor, pharmaceutical target, platelets, receptor, red blood cells, sickle cell anemia

EAST LANSING, Mich. — A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists.

A team led by Dana Spence of MSU’s Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1. By creating a new, simple method to study it after blood is drawn, the team has unlocked a potential new drug target for many diseases that impact red blood cells, such as diabetes, hypertension and cystic fibrosis. (more…)

Ancient Domesticated Dog Skull Found in Siberian Cave

By Guest PostJanuary 22, 2012Scienceaccelerator mass spectrometer, altai mountains, atmospheric circulation, beam of carbon, belgium, best friend, carbon 12, carbon 13, carbon 14, carbon beam, carbon isotopes, cave, chihuahua, climate change, crowded, dog domestication, dog skull, domestication, earth, euro asia, glacial maximum, greg hodgins, half life, last glacial maximum, last ice age, lgm, man, mass spectrum, modern dogs, organic molecules, photosynthesis, plants, radioactive carbon, radiocarbon, radiocarbon age, razboinichya cave, rottweiler, Siberia, siberian mountain, teeth

*A 33,000-year-old dog skull unearthed in a Siberian mountain cave presents some of the oldest known evidence of dog domestication and, together with an equally ancient find in a cave in Belgium, indicates that modern dogs may be descended from multiple ancestors.*

If you think a Chihuahua doesn’t have much in common with a Rottweiler, you might be on to something.

An ancient dog skull, preserved in a cave in the Altai Mountains of Siberia for 33,000 years, presents some of the oldest known evidence of dog domestication and, together with equally ancient dog remains from a cave in Belgium, indicates that domestication of dogs may have occurred repeatedly in different geographic locations rather than with a single domestication event. (more…)

Biochip Measures Glucose in Saliva, Not Blood

By Guest PostJanuary 22, 2012Sciencealec roelke, americans, biochip, biological device, blood, brown university, chip, convergence, diabetics, domenico pacifici, environmental substances, glucose concentration, glucose levels, grooves, human hair, human saliva, interaction of electrons, interference, jing feng, light, light intensity, maxima and minima, measure, microfluidic channels, milligrams per deciliter, Nanotechnology, ocean waves, photons, plasmonic interferometers, steve rhieu, surface plasmon polariton, surface plasmon waves, surface plasmonics, tayhas palmore, vihang mehta, vince siu, wavelength

*Engineers at Brown University have designed a biological device that can measure glucose concentrations in human saliva. The technique could eliminate the need for diabetics to draw blood to check their glucose levels. The biochip uses plasmonic interferometers and could be used to measure a range of biological and environmental substances. Results are published in Nano Letters.*

PROVIDENCE, R.I. [Brown University] — For the 26 million Americans with diabetes, drawing blood is the most prevalent way to check glucose levels. It is invasive and at least minimally painful. Researchers at Brown University are working on a new sensor that can check blood sugar levels by measuring glucose concentrations in saliva instead.

The technique takes advantage of a convergence of nanotechnology and surface plasmonics, which explores the interaction of electrons and photons (light). The engineers at Brown etched thousands of plasmonic interferometers onto a fingernail-size biochip and measured the concentration of glucose molecules in water on the chip. Their results showed that the specially designed biochip could detect glucose levels similar to the levels found in human saliva. Glucose in human saliva is typically about 100 times less concentrated than in the blood. (more…)