Tag Archives: clinical trials

Compound in Grapes, Red Wine Could be Key to Fighting Prostate Cancer

MU researcher finds that prostate tumor cells are more susceptible to treatment after being exposed to resveratrol, a compound found in grape skins and red wine.

Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several beneficial effects on human health, including cardiovascular health and stroke prevention. Now, a University of Missouri researcher has discovered that the compound can make prostate tumor cells more susceptible to radiation treatment, increasing the chances of a full recovery from all types of prostate cancer, including aggressive tumors.

“Other studies have noted that resveratrol made tumor cells more susceptible to chemotherapy, and we wanted to see if it had the same effect for radiation therapy,” said Michael Nicholl, an assistant professor of surgical oncology in the MU School of Medicine. “We found that when exposed to the compound, the tumor cells were more susceptible to radiation treatment, but that the effect was greater than just treating with both compounds separately.” (more…)

Read More

Vision Improves Modestly in Patients after Human Embryonic Stem Cells Transplants

Researchers at UCLA’s Jules Stein Eye Institute and colleagues who successfully transplanted specialized retinal cells derived from human embryonic stem cells into the eyes of two legally blind patients report that the transplants appear safe and that both patients have experienced modest improvement in their vision.

The preliminary findings, published online Jan. 23 in the journal The Lancet, represent a milestone in the therapeutic use of stem cells and may pave the way for a new therapy to treat eye diseases, the researchers said. Because this is the first time physicians have applied the power of regenerative medicine to eye disease, the clinical trials are being watched closely by scientists, stem-cell therapy advocates and the public. (more…)

Read More

Replacing Body Parts Now More Than ‘Science Fiction’

If Dr. Laura Niklason has her way, vascular surgeons will someday be able to pull human veins off a shelf, whenever they want, to save lives.

Niklason is a pioneer in the science — and art — of tissue-engineered replacement of human body components. Last year, she led a research team that successfully implanted tissue-engineered lungs, cultured in vitro, in adult rats. For short intervals of time, the engineered lungs exchanged oxygen and carbon dioxide similarly to natural lungs. (more…)

Read More