Tag Archives: biochip

New Biochip Holds Great Promise for Quickly Triaging People after Radiation Exposure

Berkeley Lab scientists have helped to develop a tiny chip that has big potential for quickly determining whether someone has been exposed to dangerous levels of ionizing radiation.

The first-of-its-kind chip has an array of nanosensors that measure the concentrations of proteins that change after radiation exposure.

Although still under development, the technology could lead to a hand-held device that “lights up” if a person needs medical attention in the aftermath of an incident involving radiation. Initial tests on mice found that the technology only requires a drop of blood, measures radiation dose in minutes, and yields results up to seven days after exposure. (more…)

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Biochip Measures Glucose in Saliva, Not Blood

*Engineers at Brown University have designed a biological device that can measure glucose concentrations in human saliva. The technique could eliminate the need for diabetics to draw blood to check their glucose levels. The biochip uses plasmonic interferometers and could be used to measure a range of biological and environmental substances. Results are published in Nano Letters.*

PROVIDENCE, R.I. [Brown University] — For the 26 million Americans with diabetes, drawing blood is the most prevalent way to check glucose levels. It is invasive and at least minimally painful. Researchers at Brown University are working on a new sensor that can check blood sugar levels by measuring glucose concentrations in saliva instead.

The technique takes advantage of a convergence of nanotechnology and surface plasmonics, which explores the interaction of electrons and photons (light). The engineers at Brown etched thousands of plasmonic interferometers onto a fingernail-size biochip and measured the concentration of glucose molecules in water on the chip. Their results showed that the specially designed biochip could detect glucose levels similar to the levels found in human saliva. Glucose in human saliva is typically about 100 times less concentrated than in the blood. (more…)

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