Berkeley Lab scientists have helped to develop a tiny chip that has big potential for quickly determining whether someone has been exposed to dangerous levels of ionizing radiation.
The first-of-its-kind chip has an array of nanosensors that measure the concentrations of proteins that change after radiation exposure.
Although still under development, the technology could lead to a hand-held device that “lights up” if a person needs medical attention in the aftermath of an incident involving radiation. Initial tests on mice found that the technology only requires a drop of blood, measures radiation dose in minutes, and yields results up to seven days after exposure. (more…)
University of Colorado Boulder astronomers targeting one of the brightest quasars glowing in the universe some 11 billion years ago say “sideline quasars” likely teamed up with it to heat abundant helium gas billions of years ago, preventing small galaxy formation.
CU-Boulder Professor Michael Shull and Research Associate David Syphers used the Hubble Space Telescope to look at the quasar — the brilliant core of an active galaxy that acted as a “lighthouse” for the observations — to better understand the conditions of the early universe. The scientists studied gaseous material between the telescope and the quasar with a $70 million ultraviolet spectrograph on Hubble designed by a team from CU-Boulder’s Center for Astrophysics and Space Astronomy. (more…)
Berkeley Lab research could lead to new ways to ID women who have higher risk of breast cancer from low-dose radiation
Scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified tissue mechanisms that may influence a woman’s susceptibility or resistance to breast cancer after exposure to low-dose ionizing radiation, such as the levels used in full-body CT scans and radiotherapy.
The research could lead to new ways to identify women who have higher or lower risks of breast cancer from low-dose radiation. Such a predictive tool could help guide the treatment of cancer patients who may be better served by non-radiation therapies. (more…)
*Berkeley Lab Researchers Find Evidence Suggesting Risk May Not Be Proportional to Dose at Low Dose Levels*
Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation – the linear-no-threshold hypothesis or LNT – which holds that risk is directly proportional to dose at all levels of irradiation.
“Our data show that at lower doses of ionizing radiation, DNA repair mechanisms work much better than at higher doses,” says Mina Bissell, a world-renowned breast cancer researcher with Berkeley Lab’s Life Sciences Division. “This non-linear DNA damage response casts doubt on the general assumption that any amount of ionizing radiation is harmful and additive.” (more…)
