Tag Archives: mathematical modeling

‘Tiger stripes’ underneath Antarctic glaciers slow the flow

Narrow stripes of dirt and rock beneath massive Antarctic glaciers create friction zones that slow the flow of ice toward the sea, researchers at Princeton University and the British Antarctic Survey have found. Understanding how these high-friction regions form and subside could help researchers understand how the flow of these glaciers responds to a warming climate.

Just as no-slip strips on flooring prevent people from slipping on a wet floor, these ribs or “tiger stripes” — named in reference to Princeton’s tiger mascot — provide friction that hinders the glaciers from slipping along the underlying bed of rock and sediment, the researchers report online in the journal Science. (more…)

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New Take on Impacts of Low Dose Radiation

*Berkeley Lab Researchers Find Evidence Suggesting Risk May Not Be Proportional to Dose at Low Dose Levels*

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation – the linear-no-threshold hypothesis or LNT – which holds that risk is directly proportional to dose at all levels of irradiation.

“Our data show that at lower doses of ionizing radiation, DNA repair mechanisms work much better than at higher doses,” says Mina Bissell, a world-renowned breast cancer researcher with Berkeley Lab’s Life Sciences Division. “This non-linear DNA damage response casts doubt on the general assumption that any amount of ionizing radiation is harmful and additive.” (more…)

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The Genographic Project Confirms Humans Migrated Out of Africa through Arabia

*New analytical method approaches the unstudied 99% of the human genome*

WASHINGTON, D.C., – 02 Nov 2011: Evolutionary history shows that human populations likely originated in Africa, and the Genographic Project, the most extensive survey of human population genetic data to date, suggests where they went next. A study by the Project finds that modern humans migrated out of Africa via a southern route through Arabia, rather than a northern route by way of Egypt. These findings will be highlighted today at a conference at the National Geographic Society.

National Geographic and IBM’s Genographic Project scientific consortium have developed a new analytical method that traces the relationship between genetic sequences from patterns of recombination – the process by which molecules of DNA are broken up and recombine to form new pairs. Ninety-nine percent of the human genome goes through this shuffling process as DNA is being transmitted from one generation to the next. These genomic regions have been largely unexplored to understand the history of human migration. (more…)

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