Tag Archives: heart disease

UCLA Study Looks at Why Heart Attacks Cause so Much More Damage in Late Pregnancy

Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.

While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new UCLA study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females.

The research is published in the July edition of the peer-reviewed journal Basic Research in Cardiology. (more…)

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Can Inflammation Predict Heart Disease and Stroke?

Can Inflammation Predict Heart Disease and Stroke?

Groundbreaking research may be able to help predict how likely it is that a person will have heart disease or a stroke in the future. Studies have linked inflammation to the risk of cardiovascular disease because of the association between the release of C-Reactive Protein (CRP) and heart disease.

What is C-Reactive Protein (CRP)?

The National Institute of Health explains that CRP is a protein that is released when there is inflammation present in the body. The liver produces the protein and a blood test can be done to find out how much CRP is present in a person’s body.

What is inflammation?

John W. Kimball maintains a website describing in depth how inflammation develops in the body. Inflammation develops as a result of injury to the body. It can often be recognized by swelling and redness at the site of inflammation and may be accompanied by pain. Although inflammation often occurs on the surface of the skin, it can also occur internally. (more…)

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Number of Dead California Sea Otters Recovered in 2011 a Record High

*Evidence Builds for White Shark Factor in Otter Mortality*

SANTA CRUZ, Calif. — The California or southern sea otter (Enhydra lutris nereis) appears to be experiencing an unprecedented increase in mortality from attacks by sharks, according to federal and state scientists. 

Since 1968, biologists and veterinarians at the U.S. Geological Survey and California Department of Fish and Game have documented and examined all reported sea otter “strandings” —  counting the number of dead, sick or injured sea otters recovered along California’s coast each year. (more…)

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How Good Cholesterol Turns Bad

Berkeley Lab Researchers Find New Evidence on How Cholesterol Gets Moved from HDLs to LDLs

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have found new evidence to explain how cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol from “good” high density lipoproteins (HDLs) to “bad” low density lipoproteins (LDLs). These findings point the way to the design of safer, more effective next generation CETP inhibitors that could help prevent the development of heart disease. (more…)

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They Know The Drool

*The search for biomarkers of disease in spit*

It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.

A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease. (more…)

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Gene Research Sheds Light on Timing of Menopause

An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause.

These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease.

Menopause  is a major hormonal change that affects most women when they are in their early 50s. The timing of menopause can have a huge impact on fertility, as well as influencing the risk of a range of common diseases such as breast cancer. It has been known for some time that genetic factors influenced the onset of menopause, however until recently very few genes had been identified.

In the new study, published in the journal Nature Genetics on 22 January 2012, Dr Anna Murray, University of Exeter, Peninsula College of Medicine and Dentistry (PCMD) Dr John Perry, PCMD and WTCHG, University of Oxford, and dozens of international collaborators, examined the genomes of over 50,000 women. They identified 13 novel gene regions associated with menopause onset, and confirmed four previously identified. Most of the 17 regions include genes related to DNA damage/repair or the immune system, whilst others are linked to hormonal regulation. (more…)

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Yale Researchers Find Genetic Link Between Heart Disease and Brain Aneurysms

Yale School of Medicine researchers have discovered that a variant of a gene linked to heart disease also increases the risk of deadly aneurysms of blood vessels in the brain. The discovery of this link raises hopes for new treatments for intracranial aneurysms, which affect more than a half million people worldwide annually.

“Existing drugs already target this common pathway and, in the future, could help treat or prevent aneurysms in people who are at risk,” said Murat Gunel, professor of neurosurgery, genetics and neurobiology and senior author of the study, published the week of Nov. 21 in the Proceedings of the National Academy of Sciences. (more…)

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