Tag Archives: melanoma

UCLA Researchers Further Refine ‘Nanovelcro’ Device to Grab Single Cancer Cells from Blood

Improvement enables ‘liquid biopsies’ for metastatic melanoma

Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients’ tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis.

Circulating tumor cells, or CTCs, play a crucial role in cancer metastasis, spreading from tumors to other parts of the body, where they form new tumors. When these cells are isolated from the blood early on, they can provide doctors with critical information about the type of cancer a patient has, the characteristics of the individual cancer and the potential progression of the disease. Doctors can also tell from these cells how to tailor a personalized treatment to a specific patient. (more…)

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They Know The Drool

*The search for biomarkers of disease in spit*

It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.

A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease. (more…)

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MU Researcher’s Photoacoustic Device Finds Cancer Cells Before They Become Tumors

*Commercial production will allow scientists, academia opportunity for use in cancer studies*

COLUMBIA, Mo. – Early detection of melanoma, the most aggressive skin cancer, is critical because melanoma will spread rapidly throughout the body. Now, University of Missouri researchers are one step closer to melanoma cancer detection at the cellular level, long before tumors have a chance to form. Commercial production of a device that measures melanoma using photoacoustics, or laser-induced ultrasound, will soon be available to scientists and academia for cancer studies. The commercial device also will be tested in clinical trials to provide the data required to obtain U.S. Food and Drug Administration approval for early diagnosis of metastatic melanoma and other cancers. (more…)

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Yale Scientists Identify Gene That Controls The Spread of Melanoma

Yale Cancer Center researchers have identified a gene in melanoma that can dramatically affect the spread of the disease. The study, published in the journal Cancer Cell, provides new insight into how melanoma metastasizes in patients with advanced disease, and which organs are most likely to be affected. These findings could potentially lead to new drug treatments.

Malignant melanoma is the most deadly form of skin cancer, accounting for 80 percent of all skin cancer deaths. Nearly all melanoma deaths are a result of metastasis, which can occur early in the course of tumor growth in the skin. (more…)

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Sun Safety: Facts about Skin Cancer and Tips on Preventing It

With summer upon us, Yale Medical Group physicians have an urgent warning: Be sun smart. Practicing good sun protection, including the use of sunscreen, could save your life, they say.

“You don’t want to go crawl under a rock or hide in the basement,” says dermatologist Dr. David Leffell, CEO of Yale Medical Group and a member of Yale Cancer Center. “You want to be active and that usually is best done outdoors — simply use moderation and common sense.” (more…)

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More Sun Safety: A Young Woman’s Battle Against Melanoma

Cases of melanoma, the deadliest form of skin cancer, are rising dramatically, despite the known link to outdoor or indoor exposure to ultraviolet rays. In fact, it is expected that more new cases of skin cancer will be diagnosed this year than breast, prostate, lung and colon cancer combined.

“Skin cancer is the most preventable cancer, but because many people still don’t understand the dangers of the sun and indoor tanning machines, melanoma has become one of the most common cancers among young adults,” says Dr. David J. Leffell, CEO of Yale Medical Group, a member of Yale Cancer Center and chief of dermatologic surgery and cutaneous oncology at Yale School of Medicine. (more…)

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