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You Are What You Eat: Low-Fat Diet with Fish Oil Slows Growth of Prostate Cancer Cells

By Guest PostOctober 28, 2011Health, Scienceamericans, antibody, cancer cell growth, cell cycle progression, composition of cell membranes, corn oil, evaluated blood samples, fish oil supplement diet, fish oil supplements, growth of prostate cancer cells, jonsson comprehensive cancer center, ki 67, low fat diet, malignant cell proliferation, omega 6 fatty acids, omega-3 fatty acids, progression of prostate cancer, proliferation, prostate, prostate tissue, prostatectomy, protein, rate of prostate cancer cell division, targeted organ, test tube, william aronson

Men who ate a low-fat diet with fish oil supplements for four to six weeks before having their prostate removed had slower cancer-cell growth in their prostate tissue than men who ate a traditional, high-fat Western diet, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

The researchers also found a change in the composition of cell membranes in both healthy cells and cancer cells in the prostates of men on the low-fat, fish oil–supplement diet. The membranes had heightened levels of omega-3 fatty acids from fish oil and decreased levels of omega-6 fatty acids from corn oil, which may directly affect the biology of the cells, though further studies are needed, said Dr. William Aronson, the study’s first author and a researcher with the Jonsson Cancer Center. (more…)

Researchers Develop System that Finds Prostate Cancer Metastases Earlier

By Guest PostOctober 2, 2011Health, Scienceandrogen deprivation therapy, bone metastasis model, bony metastasis, castration resistant prostate cancer, conventional imaging techniques, gene based imaging system, hormone treatment, jonsson comprehensive cancer center, lily wu, metastatic prostate cancers, oncologists, PET, positron emission tomography scanning, prostate, prostate cancer, prostate specific enhancing sequence, pses, tumor growth rate, ziyue karen jiang

Researchers at UCLA’s Jonsson Comprehensive Cancer Center have developed a way to image the spread of a dangerous form of prostate cancer earlier than today’s conventional imaging techniques. The new method may allow oncologists to find and treat metastases more quickly and give patients a better chance at survival.

The gene-based imaging system targets castration-resistant prostate cancer, an aggressive form of the disease that has become resistant to the hormone treatment known as androgen-deprivation therapy. Once this treatment no longer works, the cancer will progress within 12 to 18 months, and the prognosis becomes grim, said senior study author Dr. Lily Wu, a professor of molecular and medical pharmacology and a Jonsson Cancer Center researcher. (more…)

Researchers Discover Way to ‘Amp Up’ Power of Killer T Cells in Immune System

By Guest PostMay 22, 2011Health, Scienceanti tumor function, brain, cd8 cells, cd8 t cells, cytokines, dendritic cell vaccines, dominique lisiero, fight viruses, glioblastoma, il-12, imiquimod, immune system, interleukin-12, jonsson comprehensive cancer center, killer t cells, melanoma, models of metastatic melanoma, robert prins, tlrs, toll like receptors

Researchers at UCLA’s Jonsson Comprehensive Cancer Center have discovered a way to “amp up” the power of killer T cells known as CD8 cells in the immune system, making them more functional for longer periods of time and boosting their ability to multiply and expand within the body to fight melanoma.

The study, done in mouse models of metastatic melanoma that had spread to the brain, has important clinical implications, as the method could improve the cancer-killing power of experimental immunotherapies being tested now for various cancers, including deadly glioblastoma and metastatic melanoma, both of which are very difficult to treat successfully. (more…)

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You Are What You Eat: Low-Fat Diet with Fish Oil Slows Growth of Prostate Cancer Cells

Researchers Develop System that Finds Prostate Cancer Metastases Earlier

Researchers Discover Way to ‘Amp Up’ Power of Killer T Cells in Immune System