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You Are What You Eat: Low-Fat Diet with Fish Oil Slows Growth of Prostate Cancer Cells

By Guest PostOctober 28, 2011Health, Scienceamericans, antibody, cancer cell growth, cell cycle progression, composition of cell membranes, corn oil, evaluated blood samples, fish oil supplement diet, fish oil supplements, growth of prostate cancer cells, jonsson comprehensive cancer center, ki 67, low fat diet, malignant cell proliferation, omega 6 fatty acids, omega-3 fatty acids, progression of prostate cancer, proliferation, prostate, prostate tissue, prostatectomy, protein, rate of prostate cancer cell division, targeted organ, test tube, william aronson

Men who ate a low-fat diet with fish oil supplements for four to six weeks before having their prostate removed had slower cancer-cell growth in their prostate tissue than men who ate a traditional, high-fat Western diet, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

The researchers also found a change in the composition of cell membranes in both healthy cells and cancer cells in the prostates of men on the low-fat, fish oil–supplement diet. The membranes had heightened levels of omega-3 fatty acids from fish oil and decreased levels of omega-6 fatty acids from corn oil, which may directly affect the biology of the cells, though further studies are needed, said Dr. William Aronson, the study’s first author and a researcher with the Jonsson Cancer Center. (more…)

Two Genetic Variations Predict Second Cancers after Radiation Treatment for Children with Hodgkin’s

By Guest PostJuly 28, 2011Health, Scienceandrew skol, apoptosis, cancer types, cells, differentiation, fundamental cellular processes, gene, genetic variations, hodgkins lymphoma, hodgkins survivors, kenan onel, nature medicine, prdm1, prmd1 gene, proliferation, radiation and chemotherapy, radiation induced second cancers, radiation therapy, sarah jackson, single nucleotide polymorphisms, timothy best, treatable cancers

A genome-wide association study published in the August issue of Nature Medicine has found two tiny genetic variations that can predict which patients with Hodgkin’s lymphoma are most likely to develop radiation-induced second cancers years after treatment. Knowing in advance who is at risk could help physicians tailor treatment to reduce the risks for patients who are most susceptible to long-term damage.

Hodgkin’s lymphoma is one of the most treatable cancers, with more than 90 percent of patients surviving after a combination of radiation and chemotherapy. But nearly 20 percent of patients treated as children develop a second cancer within 30 years. The younger the patients are when treated and the higher the radiation dose, the greater the risk. This late side effect of treatment is the second leading cause of death for long-term Hodgkin’s survivors. (more…)

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You Are What You Eat: Low-Fat Diet with Fish Oil Slows Growth of Prostate Cancer Cells

Two Genetic Variations Predict Second Cancers after Radiation Treatment for Children with Hodgkin’s