corn oil – Shamskm: A site to exchange knowledge and solutions

Exposed To Phthalates as Fetuses, Female Mice Have Altered Reproductive Lives

By Guest PostMarch 20, 2012Sciencebenjamin moyer, brown university, cell growth, chemical, concern list, corn oil, david orenstein, dehp, doses of phthalates, exposure scenario, female mouse fetuses, health effect, in utero, industrial chemical, mammary glands, mary hixon, mehp, mice, organism, Phthalates, plastics, precancerous lesions, reproductive lifespan, reproductive system, toxicology

Many environmental and public health officials are concerned about the potential health effects of phthalates, which are common chemicals used to make plastics softer and more pliable. In the first study to examine what effect in utero doses of phthalates have on the reproductive system of mice, Brown University toxicologists found that extremely high doses were associated with significant changes, such as a shortened reproductive lifespan and abnormal cell growth in mammary glands.

PROVIDENCE, R.I. [Brown University] — Female mouse fetuses exposed to very high doses of a common industrial chemical that makes plastics more pliable develop significant reproductive alterations and precancerous lesions as they grow up, according to a new toxicology study conducted at Brown University.

The administered doses of MEHP, the chemical that results when animals metabolize the industrial phthalate DEHP, were much higher than any normal environmental exposure that people or animals would encounter, said Mary Hixon, assistant professor of pathology and laboratory medicine (research) in The Warren Alpert Medical School of Brown University and a study co-author. (more…)

You Are What You Eat: Low-Fat Diet with Fish Oil Slows Growth of Prostate Cancer Cells

By Guest PostOctober 28, 2011Health, Scienceamericans, antibody, cancer cell growth, cell cycle progression, composition of cell membranes, corn oil, evaluated blood samples, fish oil supplement diet, fish oil supplements, growth of prostate cancer cells, jonsson comprehensive cancer center, ki 67, low fat diet, malignant cell proliferation, omega 6 fatty acids, omega-3 fatty acids, progression of prostate cancer, proliferation, prostate, prostate tissue, prostatectomy, protein, rate of prostate cancer cell division, targeted organ, test tube, william aronson

Men who ate a low-fat diet with fish oil supplements for four to six weeks before having their prostate removed had slower cancer-cell growth in their prostate tissue than men who ate a traditional, high-fat Western diet, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

The researchers also found a change in the composition of cell membranes in both healthy cells and cancer cells in the prostates of men on the low-fat, fish oil–supplement diet. The membranes had heightened levels of omega-3 fatty acids from fish oil and decreased levels of omega-6 fatty acids from corn oil, which may directly affect the biology of the cells, though further studies are needed, said Dr. William Aronson, the study’s first author and a researcher with the Jonsson Cancer Center. (more…)

Tag Archives: corn oil

Exposed To Phthalates as Fetuses, Female Mice Have Altered Reproductive Lives

You Are What You Eat: Low-Fat Diet with Fish Oil Slows Growth of Prostate Cancer Cells