ANN ARBOR — Scientists have known for nearly a century that cold-blooded animals, such as worms, flies and fish all live longer in cold environments, but have not known exactly why.
Researchers at the University of Michigan Life Sciences Institute have identified a genetic program that promotes longevity of roundworms in cold environments—and this genetic program also exists in warm-blooded animals, including humans. (more…)
A team of materials scientists at Harvard University and the University of Exeter has invented a new fibre which changes colour when stretched. Inspired by nature, the researchers identified and replicated the unique structural elements, which create the bright iridescent blue colour of a tropical plant’s fruit.
The multilayered fibre, described in the journal Advanced Materials, could lend itself to the creation of smart fabrics that visibly react to heat or pressure.
“Our new fibre is based on a structure we found in nature, and through clever engineering we’ve taken its capabilities a step further,” says lead author Dr Mathias Kolle, a postdoctoral fellow at the Harvard School of Engineering and Applied Sciences (SEAS). “The plant, of course, cannot change colour. By combining its structure with an elastic material, however, we’ve created an artificial version that passes through a full rainbow of colours as it’s stretched.” (more…)
Initial results in mice could lead to new way to fight neurodegenerative diseases
There’s new hope in the fight against Huntington’s disease. A group of researchers that includes scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.
The compound is a synthetic antioxidant that targets mitochondria, an organelle within cells that serves as a cell’s power plant. Oxidative damage to mitochondria is implicated in many neurodegenerative diseases including Alzheimer’s, Parkinson’s, and Huntington’s. (more…)
Scientists now have a better understanding of how precise memories are formed thanks to research led by Prof. Jean-Claude Lacaille of the University of Montreal’s Department of Physiology. “In terms of human applications, these findings could help us to better understand memory impairments in neurodegenerative disorders like Alzheimer’s disease,” Lacaille said. The study looks at the cells in our brains, or neurons, and how they work together as a group to form memories.
Chemical receptors at neuron interconnections called synapses enable these cells to form electrical networks that encode memories, and neurons are classified into two groups according to the type of chemical they produce: excitatory, who produce chemicals that increase communication between neurons, and inhibitory, who have the opposite effect, decreasing communication. “Scientists knew that inhibitory cells enable us to refine our memories, to make them specific to a precise set of information,” Lacaille explained. “Our findings explain for the first time how this happens at the molecular and cell levels.” (more…)
If you throw a rubber balloon filled with water against a wall, it will spread out and deform on impact, while the same balloon filled with honey, which is more viscous, will deform much less. If the balloon’s elastic rubber was stiffer, an even smaller change in shape would be observed.
By simply analyzing how much a balloon changes shape upon hitting a wall, you can uncover information about its physical properties.
Although cells are not simple sacks of fluid, they also contain viscous and elastic properties related to the membranes that surround them; their internal structural elements, such as organelles; and the packed DNA arrangement in their nuclei. Because variations in these properties can provide information about cells’ state of activity and can be indicative of diseases such as cancer, they are important to measure. (more…)
EAST LANSING, Mich. — Researchers at Michigan State University have shown a prebiotic may help the body’s own natural killer cells fight bacterial infection and reduce inflammation, greatly decreasing the risk of colon cancer.
Prebiotics are fiber supplements that serve as food for the trillions of tiny bacteria living in the gut. When taken, they can stimulate the growth of the “good” bacteria. The evolution of prebiotic supplements (as well as probiotics, which are actual bacteria ingested into the system) provide new therapeutic targets for researchers and physicians. (more…)
EAST LANSING, Mich. — American students need a dramatically new approach to improve how they learn science, says a noted group of scientists and educators led by Michigan State University professor William Schmidt.
After six years of work, the group has proposed a solution. The 8+1 Science concept calls for a radical overhaul in K-12 schools that moves away from memorizing scientific facts and focuses on helping students understand eight fundamental science concepts. The “plus one” is the importance of inquiry, the practice of asking why things happen around us – and a fundamental part of science. (more…)
Yale University researchers have discovered a key cellular mechanism that may help the brain control how much we eat, what we weigh, and how much energy we have.
The findings, published in the Feb. 28 issue of the Journal of Neuroscience, describe the regulation of a family of cells that project throughout the nervous system and originate in an area of the brain call the hypothalamus, which has been long known to control energy balances. (more…)
