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Cognitive Behavioural Therapy Proves Effective at Reducing Depression in People Who Have not Responded to Antidepressants

By Guest PostDecember 12, 2012Healthantidepressant medication, antidepressants, australia, bristol, cbt, chris williams, cobait team, cognitive behavioural therapy, controlled trial, depression, emer oneill, exeter, first line treatment, glasgow, john campbell, mood disorders centre, nicola wiles, patients, psychological treatments, symptoms, talking therapy, treatment, uk, universities, willem kuyken, World Health Organisation

Antidepressants are the most widely used treatment for people with moderate to severe depression.

However, up to two thirds of people with depression don’t respond fully to this type of treatment. New findings have shown cognitive behavioural therapy (CBT), provided in addition to usual care, can reduce symptoms of depression and help improve patients’ quality of life.

This is the first large-scale trial to test the effectiveness of CBT – a type of talking psychotherapy- given in addition to usual care that includes antidepressants. The National Institute for Health Research Health Technology Assessment (NIHR HTA)-funded CoBalT study aimed to determine the best ‘next step’ treatment for people whose depression had not responded to medication alone. (more…)

Berkeley Lab Scientists Help Develop Promising Therapy for Huntington’s Disease

By Guest PostNovember 11, 2012Healthalzheimers, antidepressants, bacterial membrane, berkeley lab, cells, cerebral cortex, chemist, coenzyme q, cognitive decline, compound, cynthia mcmurray, DNA, genetic disorder, genetic mutation, huntingtons disease, loss, mice, mitochondria, mitochondrial function, molecules, motor coordination, motor skills, muscle coordination, neurodegenerative diseases, neuron, organelle, oxidative damage, parkinson's, peter wipf, pittsburgh, power plant, reactive oxygen species, striatum, suppress, survival, symptoms, synthetic antioxidant, university, untreated neuronal cultures, vitamin e, xjb 5 131, xjb treated mice, zhiyin xun

Initial results in mice could lead to new way to fight neurodegenerative diseases

There’s new hope in the fight against Huntington’s disease. A group of researchers that includes scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.

The compound is a synthetic antioxidant that targets mitochondria, an organelle within cells that serves as a cell’s power plant. Oxidative damage to mitochondria is implicated in many neurodegenerative diseases including Alzheimer’s, Parkinson’s, and Huntington’s. (more…)

Tag Archives: antidepressants

Cognitive Behavioural Therapy Proves Effective at Reducing Depression in People Who Have not Responded to Antidepressants

Berkeley Lab Scientists Help Develop Promising Therapy for Huntington’s Disease