Tag Archives: hormone

Elusive leptin

Researchers find first evidence of fat-regulating hormone in avian species

Since leptin was discovered 20 years ago, more than 115,000 papers have been published on this protein in humans, and another 5,000 have appeared on leptin in mice.

Leptin’s popularity is not surprising, as the hormone is the principal marker for the development of morbid obesity in humans. Leptin and its receptor play critical roles in the control of food intake and energy expenditure, thereby affecting body weight, abdominal fatness, thermogenesis, insulin sensitivity, and lipid metabolism. (more…)

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Injectable Nano-Network Controls Blood Sugar in Diabetics for Days at a Time

In a promising development for diabetes treatment, researchers have developed a network of nanoscale particles that can be injected into the body and release insulin when blood-sugar levels rise, maintaining normal blood sugar levels for more than a week in animal-based laboratory tests. The work was done by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, the Massachusetts Institute of Technology and Children’s Hospital Boston.

“We’ve created a ‘smart’ system that is injected into the body and responds to changes in blood sugar by releasing insulin, effectively controlling blood-sugar levels,” says Dr. Zhen Gu, lead author of a paper describing the work and an assistant professor in the joint biomedical engineering program at NC State and UNC Chapel Hill. “We’ve tested the technology in mice, and one injection was able to maintain blood sugar levels in the normal range for up to 10 days.” (more…)

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Breastfeeding: Not only for young teens

When a teen mom is considering breastfeeding, it may be a tough task for her to break misconceptions, she has about breastfeeding. For example, many teens prefer bottle feeding as a healthier choice over breast feeding. They also believe that their breasts will lose their shape and it is “old school.” Teen moms, just like adults consider many factors when choosing breastfeeding.

Breastfeeding is by far one of the most natural attributes of the human body. Breastfeeding is a nature’s gift and has its own benefits:

· According to research, when teen moms breastfeed their baby immediately after delivery, the uterus slowly contracts reducing the risk of post-labor hemorrhage. Also, nursing helps you to slowly regain your per-pregnancy weight, which often results in shedding off those extra pounds. Breastfeeding when done the right way, slows periods, which acts as a effective form of birth control. This is really beneficial for teen moms who cannot access other forms of birth control during breastfeeding. Breastfeeding also reduces the chances of developing ovarian cancer and breast cancer. (more…)

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Scientists Reveal Quirky Feature of Lyme Disease Bacteria

Unlike most organisms, they don’t need iron, but they crave manganese

Scientists have confirmed that the pathogen that causes Lyme Disease—unlike any other known organism—can exist without iron, a metal that all other life needs to make proteins and enzymes. Instead of iron, the bacteria substitute manganese to make an essential enzyme, thus eluding immune system defenses that protect the body by starving pathogens of iron.

To cause disease, Borrelia burgdorferi requires unusually high levels of manganese, scientists at Johns Hopkins University (JHU), Woods Hole Oceanographic Institution (WHOI), and the University of Texas reported. Their study, published March 22, 2013, in The Journal of Biological Chemistry, may explain some mysteries about why Lyme Disease is slow-growing and hard to detect and treat. The findings also open the door to search for new therapies to thwart the bacterium by targeting manganese. (more…)

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Cycling May Negatively Affect Male Reproductive Health, UCLA Study Finds

A study by researchers at the UCLA School of Nursing has found that serious male cyclists may experience hormonal imbalances that could affect their reproductive health.

The study, “Reproductive Hormones and Interleukin-6 in Serious Leisure Male Athletes,” was recently published in the European Journal of Applied Physiology.

To date, an extensive amount of research has been done documenting the positive effects of long-term exercise on health. Yet while moderate exercise can lead to enhanced cardiovascular and metabolic function and reduced body fat, studies have shown that ultra-endurance levels of exercise can also adversely affect the neuroendocrine system and reproductive health. (more…)

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Plant Scientists Find Mechanism That Gives Plants ‘Balance’

EAST LANSING, Mich. — When a plant goes into defense mode in order to protect itself against harsh weather or disease, that’s good for the plant, but bad for the farmer growing the plant. Bad because when a plant acts to defend itself, it turns off its growth mechanism.

But now researchers at Michigan State University, as part of an international collaboration, have figured out how plants can make the “decision” between growth and defense, a finding that could help them strike a balance – keep safe from harm while continuing to grow. (more…)

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UCLA Scientists Design Experimental Treatment for Iron-Overload Diseases

Iron overload is a common condition affecting millions of people worldwide. Excess iron in the body is toxic, and deposits can cause damage to the liver, heart and other organs. Current treatments, researchers say, are not ideal and have significant side effects.

Iron in the body is regulated by a hormone called hepcidin, and a deficiency in this hormone can cause the iron overload seen in genetic disorders like hereditary hemochromatosis and Cooley’s anemia. (more…)

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