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Researchers discover hormone that controls supply of iron in red blood cell production

By Guest PostJuly 18, 2014Healthbone marrow, control, failure behavior, fairness, fake news, level of rigidity, material failure, media propaganda, production, red blood cell, sibylle schroer, strassenbeleuchtung, tomas ganz, verlust der nacht, why materials break

Findings could lead to treatments for blood disorders associated with both iron deficiencies and overloads

A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production.

Iron is an essential functional component of hemoglobin, the molecule that transports oxygen throughout the body. Using a mouse model, researchers found that erythroferrone is made by red blood-cell progenitors in the bone marrow in order to match iron supply with the demands of red blood-cell production. Erythroferrone is greatly increased when red blood-cell production is stimulated, such as after bleeding or in response to anemia. (more…)

UCLA Scientists Design Experimental Treatment for Iron-Overload Diseases

By Guest PostNovember 6, 2011Health, Scienceamino acids, bo qiao, change in iron flow in the body, cooley anemia, damage, effects of hepcidin in mice, elizabeta nemeth, emilio ramos, excess iron in the body, ferroportin, genetic disorders, gloria c preza, heart, hepcidin, hereditary hemochromatosis, hormone, iron overload, iron overload diseases, iron regulating activity, iron regulation, liver, minihepcidins, molecules, organs, piotr ruchala, therapy, tomas ganz, toxic

Iron overload is a common condition affecting millions of people worldwide. Excess iron in the body is toxic, and deposits can cause damage to the liver, heart and other organs. Current treatments, researchers say, are not ideal and have significant side effects.

Iron in the body is regulated by a hormone called hepcidin, and a deficiency in this hormone can cause the iron overload seen in genetic disorders like hereditary hemochromatosis and Cooley’s anemia. (more…)

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Researchers discover hormone that controls supply of iron in red blood cell production

UCLA Scientists Design Experimental Treatment for Iron-Overload Diseases