Tag Archives: lipid metabolism

Elusive leptin

Researchers find first evidence of fat-regulating hormone in avian species

Since leptin was discovered 20 years ago, more than 115,000 papers have been published on this protein in humans, and another 5,000 have appeared on leptin in mice.

Leptin’s popularity is not surprising, as the hormone is the principal marker for the development of morbid obesity in humans. Leptin and its receptor play critical roles in the control of food intake and energy expenditure, thereby affecting body weight, abdominal fatness, thermogenesis, insulin sensitivity, and lipid metabolism. (more…)

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New Research Gets to the Heart of How Niacin Fights High cholesterol, Points to a New Pathway

ANN ARBOR, Mich.— High blood lipids are a big risk factor for developing heart disease, which is the leading cause of death in the United States. Approximately one of every six adult Americans has high blood cholesterol and about every 25 seconds, an American will have a heart attack, and nearly one every minute will die from it, according to the Centers for Disease Control and Prevention. (more…)

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