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New Technique Targets Specific Areas of Cancer Cells with Different Drugs

By Guest PostJanuary 8, 2014Healthadriano bellotti, cancer cell, chapel hill, conventional treatment techniques, dox, doxorubicin, drugs, enzymes, jianping zhou, large scale manufacturing, nanoparticle, new technique, north Carolina, nucleus, programmed strategy, ran mo, specific area, state university, target, tianyue jiang, zhen gu

Researchers have developed a technique for creating nanoparticles that carry two different cancer-killing drugs into the body and deliver those drugs to separate parts of the cancer cell where they will be most effective. The technique was developed by researchers at North Carolina State University and the University of North Carolina at Chapel Hill.

“In testing on laboratory mice, our technique resulted in significant improvement in breast cancer tumor reduction as compared to conventional treatment techniques,” says Dr. Zhen Gu, senior author of a paper on the research and an assistant professor in the joint biomedical engineering program at NC State and UNC-Chapel Hill. (more…)

Injectable Nano-Network Controls Blood Sugar in Diabetics for Days at a Time

By Guest PostMay 20, 2013Sciencealginate, blood sugar, blood sugar levels, bloodstream, chitosan, closed loop system, daniel anderson, dextran, diabetes patients, diabetes treatment, gluconic acid, glucose, glucose oxidase enzymes, hormone, injectable nano network, injection, insulin, massachusetts institute, material, nanoparticle cores, nanoscale particles, network, north Carolina, robert langer, seaweed, shrimp shells, state university, Technology, type 1 diabetes, unc chapel, zhen gu

In a promising development for diabetes treatment, researchers have developed a network of nanoscale particles that can be injected into the body and release insulin when blood-sugar levels rise, maintaining normal blood sugar levels for more than a week in animal-based laboratory tests. The work was done by researchers at North Carolina State University, the University of North Carolina at Chapel Hill, the Massachusetts Institute of Technology and Children’s Hospital Boston.

“We’ve created a ‘smart’ system that is injected into the body and responds to changes in blood sugar by releasing insulin, effectively controlling blood-sugar levels,” says Dr. Zhen Gu, lead author of a paper describing the work and an assistant professor in the joint biomedical engineering program at NC State and UNC Chapel Hill. “We’ve tested the technology in mice, and one injection was able to maintain blood sugar levels in the normal range for up to 10 days.” (more…)

Tiny Capsule Effectively Kills Cancer Cells

By Guest PostFebruary 19, 2013Healthbiliang hu, cancer cells, cancer treatment, cancerous cells, chapel hill, chemotherapy, functional form, gene therapies, genetic mutation, growth of tumors, healthy cells, human breast cancer, kills, laboratory mice, muxun zhao, nano today, non cancerous cells, north Carolina, nucleus, pin wang, polymer shells, protein complex, proteins, reversible polymer encapsulation, risk, self destruction, signals, strategy, tiny capsule, university, water soluble polymer, yi tang, zhen gu

Scientists create nanoscale vehicle to battle cancer without harming healthy cells

A tiny capsule invented at a UCLA lab could go a long way toward improving cancer treatment.
Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.

In a new study, published online Feb. 1 in the peer-reviewed journal Nano Today, a group led by Yi Tang, a professor of chemical and biomolecular engineering and a member of the California NanoSystems Institute at UCLA, reports developing tiny shells composed of a water-soluble polymer that safely deliver a protein complex to the nucleus of cancer cells to induce their death. The shells, which at about 100 nanometers are roughly half the size of the smallest bacterium, degrade harmlessly in non-cancerous cells. (more…)

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New Technique Targets Specific Areas of Cancer Cells with Different Drugs

Injectable Nano-Network Controls Blood Sugar in Diabetics for Days at a Time

Tiny Capsule Effectively Kills Cancer Cells