COLUMBUS, Ohio — Though scientists have long believed that complex organic molecules couldn’t survive fossilization, some 350-million-year-old remains of aquatic sea creatures uncovered in Ohio, Indiana, and Iowa have challenged that assumption.
The spindly animals with feathery arms—called crinoids, but better known today by the plant-like name “sea lily”—appear to have been buried alive in storms during the Carboniferous Period, when North America was covered with vast inland seas. Buried quickly and isolated from the water above by layers of fine-grained sediment, their porous skeletons gradually filled with minerals, but some of the pores containing organic molecules were sealed intact. (more…)
AMHERST, Mass. – Studies led by cell biologist Thomas Maresca at the University of Massachusetts Amherst are revealing new details about a molecular surveillance system that helps detect and correct errors in cell division that can lead to cell death or human diseases. Findings are reported in the current issue of the Journal of Cell Biology.
The purpose of cell division is to evenly distribute the genome between two daughter cells. To achieve this, every chromosome must properly interact with a football-shaped structure called the spindle. However, interaction errors between the chromosomes and spindle during division are amazingly common, occurring in 86 to 90 percent of chromosomes, says Maresca, an expert in mitosis. (more…)
Are you allergic to peanuts and worried there might be some in that cookie? Now you can find out using a rather unlikely source: your cell phone.
A team of researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a lightweight device called the iTube, which attaches to a common cell phone to detect allergens in food samples. The iTube attachment uses the cell phone’s built-in camera, along with an accompanying smart-phone application that runs a test with the same high level of sensitivity a laboratory would.(more…)
COLUMBIA, Mo. — Approximately 250,000 people in the United States suffer from muscular dystrophy, which occurs when damaged muscle tissue is replaced with fibrous, bony or fatty tissue and loses function. Three years ago, University of Missouri scientists found a molecular compound that is vital to curing the disease, but they didn’t know how to make the compound bind to the muscle cells. In a new study, published in the Proceedings of the National Academies of Science, MU School of Medicine scientists Yi Lai and Dongsheng Duan have discovered the missing pieces to this puzzle that could ultimately lead to a therapy and, potentially, a longer lifespan for patients suffering from the disease.
Duchenne muscular dystrophy (DMD), predominantly affecting males, is the most common type of muscular dystrophy. Patients with Duchenne muscular dystrophy have a gene mutation that disrupts the production of dystrophin, a protein essential for muscle cell survival and function. Absence of dystrophin starts a chain reaction that eventually leads to muscle cell degeneration and death. While dystrophin is vital for muscle development, the protein also needs several “helpers” to maintain the muscle tissue. One of these “helper” molecular compounds is nNOS, which produces nitric oxide that can keep muscle cells healthy after exercise. (more…)
Researchers from North Carolina State University and the University of Oregon have found a way to exploit cloud-based Web browsers, using them to perform large-scale computing tasks anonymously. The finding has potential ramifications for the security of “cloud browser” services.
At issue are cloud browsers, which create a Web interface in the cloud so that computing is done there rather than on a user’s machine. This is particularly useful for mobile devices, such as smartphones, which have limited computing power.The cloud-computing paradigm pools the computational power and storage of multiple computers, allowing shared resources for multiple users. (more…)
Sequencing the barley genome will sow many benefits
Some 10,000 years ago, people found they didn’t have to live as nomads, hunting and gathering all their food. In the Fertile Crescent, they started planting crops.
The Fertile Crescent extended from the Nile Valley and along the eastern Mediterranean Coast, through the Tigris and Euphrates valleys of Mesopotamia and down to the Persian Gulf. There, the foundation crops of the Western World were first domesticated.(more…)
The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab). Knowing the architecture of this protein, PRC2, for Polycomb Repressive Complex 2, should be a boon to its future use in the development of new and improved therapeutic drugs.
“We present a complete molecular organization of human PRC2 that offers an invaluable structural context for understanding all of the previous biochemical and functional data that has been collected on this complex,” says Berkeley Lab biophysicist Eva Nogales, an electron microscopy expert who led this research. “Our model should also be an invaluable tool for the design of new experiments aimed at asking detailed questions about the mechanisms that enable PRC2 to function and how those mechanisms might be exploited.” (more…)
The Pink Double Dandy peony, the Double Peppermint petunia, the Doubled Strawberry Vanilla lily and nearly all roses are varieties cultivated for their double flowers.
The blossoms of these and other such plants are lush with extra petals in place of the parts of the flower needed for sexual reproduction and seed production, meaning double flowers – though beautiful – are mutants and usually sterile.
The genetic interruption that causes that mutation helped scientists in the 1990s pinpoint the genes responsible for normal development of sexual organs stamens and carpels in the plant Arabidopsis thaliana, long used as a plant model by biologists. (more…)
