Tag Archives: disease

Study of HIV Increase in Pakistan Could Benefit Other Research

GAINESVILLE, Fla. — Rates of HIV have increased in Pakistan’s general population, as the virus has spread beyond at-risk groups to women and their children, according to an international team of researchers, including a University of Florida scientist.

The researchers raise concern that the transmission across subgroups into Pakistan’s general population may serve as indication that the virus may be spreading into populations within neighboring Afghanistan. The team’s epidemiological findings were published in July in the journal PLoS One. (more…)

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Breaking the Chain: ‘Molecular cap’ Blocks Processes that Lead to Alzheimer’s, HIV

A new advance by UCLA biochemists has brought scientists one step closer to developing treatments that could delay the onset of Alzheimer’s disease and prevent the sexual transmission of HIV.

The researchers report that they have designed molecular inhibitors that target specific proteins associated with Alzheimer’s disease and HIV to prevent them from forming amyloid fibers, the elongated chains of interlocking proteins that play a key role in more than two dozen degenerative and often fatal diseases. (more…)

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It Takes a Community of Soil Microbes to Protect Plants From Disease

*Berkeley Lab scientists decipher immune system for plants beneath our feet*

Those vegetables you had for dinner may have once been protected by an immune system akin to the one that helps you fight disease. Scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the Netherland’s Wageningen University found that plants rely on a complex community of soil microbes to defend themselves against pathogens, much the way mammals harbor a raft of microbes to avoid infections.

The scientists deciphered, for the first time, the group of microbes that enables a patch of soil to suppress a plant-killing pathogen. Previous research on the phenomenon of disease-suppressive soil had identified one or two pathogen-fighting microbes at work. (more…)

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Earth’s Sixth Mass Extinction: Is It Almost Here?

*Steep decline of many animal species warns that Earth is on the brink*

With the steep decline in populations of many animal species, scientists have warned that Earth is on the brink of a mass extinction like those that have occurred just five times during the past 540 million years.

Each of these “Big Five” saw three-quarters or more of all animal species go extinct.

In results of a study published in this week’s issue of journal Nature, researchers report on an assessment of where mammals and other species stand today in terms of possible extinction compared with the past 540 million years.

They find cause for hope–and alarm. (more…)

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For Longer-Life, Disease-Free Roses, NC State Researchers Insert Celery Gene

A rose by any other name would smell … like celery?

North Carolina State University research intended to extend the “vase life” of roses inserts a gene from celery inside rose plants to help fight off botrytis, or petal blight, one of the rose’s major post-harvest diseases.

Some fungal pathogens, the bad guys that infect plants, produce a sugar alcohol called mannitol that interferes with the plant’s ability to block disease like petal blight, which produces wilty, mushy petals – an effect similar to what happens to lettuce when it’s been in the crisper too long. (more…)

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Fighting Words: Violent Political Rhetoric Fuels Violent Attitudes

ANN ARBOR, Mich.— Political leaders regularly promise to “fight” for noble causes and “combat” pressing problems. They declare “war” on social problems, such as poverty, disease, drugs and terrorism.

This violent political rhetoric—whether politicians intend to or not—can enflame violent attitudes in many Americans, especially those predisposed to behave aggressively in daily life, according to new University of Michigan research involving three studies. (more…)

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Change in Temperature Uncovers Genetic Cross Talk in Plant Immunity

*University of Missouri investigators’ discovery sheds light on how plants fight off bacterial infections*

Columbia, MO — Like us, plants rely on an immune system to fight off disease. Proteins that scout out malicious bacterial invaders in the cell and communicate their presence to the nucleus are important weapons in the plant’s disease resistance strategy. Researchers at the University of Missouri recently “tapped” into two proteins’ communications with the nucleus and discovered a previously unknown level of cross talk. The discovery adds important new information about how plant proteins mediate resistance to bacteria that cause disease and may ultimately lead to novel strategies for boosting a plant’s immune system.

Special proteins in the plant, called resistance proteins, can recognize highly specific features of proteins from pathogen, called effector proteins. When a pathogen is detected, a resistance protein triggers an “alarm” that communicates the danger to the cell’s nucleus. The communication between the resistance protein and nucleus occurs through a mechanism called a signaling pathway. (more…)

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Researchers Find Cancer News May Contribute to Confusion About Cancer

New research from North Carolina State University shows that most online news stories about cancer contain language that likely contributes to public uncertainty about the disease – a significant finding, given that at least one-third of Americans seek health information online.

“Previous studies show that more than 100 million Americans seek health information online, and that their findings affect their health decisions,” says Dr. Kami Kosenko, an assistant professor of communication at NC State and co-author of a paper describing the study. “But, while people facing uncertainty about cancer issues are likely to seek out additional information, we’ve found that there are features of the information they’re seeking that may actually exacerbate the uncertainty.” (more…)

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