AUSTIN, Texas — University of Texas at Austin researchers have demonstrated a new and more effective method for regrowing blood vessels in the heart and limbs — a research advancement that could have major implications for how we treat heart disease, the leading cause of death in the Western world.
The treatment method developed by Cockrell School of Engineering Assistant Professor Aaron Baker could allow doctors to bypass surgery and instead repair damaged blood vessels simply by injecting a lipid-incased substance into a patient. Once inside the body, the substance stimulates cell growth and spurs the growth of new blood vessels from pre-existing ones. (more…)
ANN ARBOR, Mich.— Using a liquid laser, University of Michigan researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases.
Their results are published in the current edition of the German journal Angewandte Chemie. (more…)
It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.
A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease.(more…)
It is well documented that male birds seduce females using their songs, colourful plumage and courtship dances. These signals reflect male genetic quality and will be graded by the female to determine a male’s potential as a mate. The stronger the grade, the better the odds of being selected.
But this basic rule isn’t the only yardstick used by females. As surprising as it seems, birds know how to use data from their social environment to maximize their chances of reproduction. Frédérique Dubois, a professor at the Université de Montréal Department of Biological Sciences, has already demonstrated that female Zebra Finches will favour a male chosen by another female. Dubois refers to this as imitation and the use of “public information” in choosing a mate. (more…)
Treating ovarian cancer with the drug bevacizumab (“Avastin”) delays the disease and may also improve survival, according to an international clinical trial co-led by Drs. Amit Oza of the University of Toronto and Princess Margaret Hospital (PMH) and Timothy Perren of St James’s Institute of Oncology, Leeds, U.K.
The findings, published on Dec. 28 in the New England Journal of Medicine, report that the drug halted the cancer’s return for two months overall. However, for women with the highest risk disease, the delay was five to six months and in this group, the findings also indicate a strong trend to improved overall survival, which is being analysed until 2013. (more…)
*Proprotein convertases are enzymes that activate many essential proteins, but they are also implicated in many processes that cause disease. In a research review in the New England Journal of Medicine, Andrew Artenstein and Steven Opal argue that proprotein convertases are potentially rich targets for developing therapies.*
Most people have never heard of proprotein convertases, but the enzymes activate many proteins that are essential for life. Unfortunately, their fundamental role puts them in the middle of many processes that cause disease – not just cancer or athlerosclerosis, but both of those and Alzheimer’s and anthrax and the flu and an amazing variety of other maladies.
In a research review article appearing Dec. 29 in the New England Journal of Medicine, Andrew Artenstein, physician-in-chief in the Department of Medicine at Memorial Hospital, and Steven Opal, chief of infectious diseases at Memorial Hospital, argue that proprotein convertases (PCs) are potentially rich targets for developing therapies. Artenstein, who with Opal is on the faculty of the Warren Alpert School of Medicine, explained PCs to David Orenstein. (more…)
*Procedure may reduce recurrence rates, lower tumor marker levels*
Papillary thyroid cancer accounts for the majority of all thyroid malignancies, which primarily impact women. A new study indicates that routinely removing lymph nodes in the neck in these cancer patients may help prevent the disease from coming back.
When thyroid cancer metastasizes, lymph nodes in the neck may be affected, but these lymph-node tumors can be tiny and may not be detected by ultrasounds done before surgery to remove the diseased thyroid — or even during the procedure itself. (more…)
EAST LANSING, Mich. — To help keep the symptoms of muscular dystrophy at bay, doctors say patients should maintain a positive attitude and be as active as possible; complete inactivity can make the disease worse. Lucky for Mo Gerhardt, negativity and inactivity aren’t in his vocabulary.
Gerhardt, who exudes positive energy, is an academic adviser at Michigan State University, color commentator for the MSU women’s basketball team, motivational speaker, a multiple medal winner in international powerhockey (electric wheelchair hockey) and author of the new book, “Perspective from an Electric Chair.” (more…)
