One in 2,000 people in the UK are estimated to be carrying variant Creutzfeldt-Jakob disease (vCJD) proteins, according to a study led by Professor Sebastian Brandner (UCL Institute of Neurology).
The research, published in this week’s BMJ, is based on samples from more than 32,000 people and provides the most robust prevalence measure to date. (more…)
A new advance by UCLA biochemists has brought scientists one step closer to developing treatments that could delay the onset of Alzheimer’s disease and prevent the sexual transmission of HIV.
The researchers report that they have designed molecular inhibitors that target specific proteins associated with Alzheimer’s disease and HIV to prevent them from forming amyloid fibers, the elongated chains of interlocking proteins that play a key role in more than two dozen degenerative and often fatal diseases. (more…)
MADISON, Wis. – Certain lichens can break down the infectious proteins responsible for chronic wasting disease (CWD), a troubling neurological disease fatal to wild deer and elk and spreading throughout the United States and Canada, according to U.S. Geological Survey research published today in the journal PLoS ONE.
Like other “prion” diseases, CWD is caused by unusual, infectious proteins called prions. One of the best-known of these diseases is “mad cow” disease, a cattle disease that has infected humans. However, there is no evidence that CWD has infected humans. Disease-causing prions, responsible for some incurable neurological diseases of people and other diseases in animals, are notoriously difficult to decontaminate or kill. Prions are not killed by most detergents, cooking, freezing or by autoclaving, a method used to sterilize medical instruments. (more…)
