A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.
Published in the March 6 issue of the Journal of Alzheimer’s Disease, the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein. (more…)
Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed cell death. The study is in the Feb. 17 issue of Cell.
Mitochondria are cellular structures that function as “cellular power plants” because they generate most of the cell’s supply of energy. They contain DNA inherited from one’s mother. Mitochondria determine whether a cell lives or dies via the process of programmed cell death, or apoptosis. (more…)
COLUMBUS, Ohio — According to a new study, smoking causes the body to turn against its own helpful bacteria, leaving smokers more vulnerable to disease.
Despite the daily disturbance of brushing and flossing, the mouth of a healthy person contains a stable ecosystem of healthy bacteria. New research shows that the mouth of a smoker is a much more chaotic, diverse ecosystem—and is much more susceptible to invasion by harmful bacteria. (more…)
*Mechanism holds potential for improving recall in dementia patients*
Have you ever gone to the movies and forgotten where you parked the car? New UCLA research may one day help you improve your memory.
UCLA neuroscientists have demonstrated that they can strengthen memory in human patients by stimulating a critical junction in the brain. Published in the Feb. 9 edition of the New England Journal of Medicine, the finding could lead to a new method for boosting memory in patients with early Alzheimer’s disease.(more…)
AUSTIN, Texas — University of Texas at Austin researchers have demonstrated a new and more effective method for regrowing blood vessels in the heart and limbs — a research advancement that could have major implications for how we treat heart disease, the leading cause of death in the Western world.
The treatment method developed by Cockrell School of Engineering Assistant Professor Aaron Baker could allow doctors to bypass surgery and instead repair damaged blood vessels simply by injecting a lipid-incased substance into a patient. Once inside the body, the substance stimulates cell growth and spurs the growth of new blood vessels from pre-existing ones. (more…)
ANN ARBOR, Mich.— Using a liquid laser, University of Michigan researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases.
Their results are published in the current edition of the German journal Angewandte Chemie. (more…)
It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.
A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease.(more…)
It is well documented that male birds seduce females using their songs, colourful plumage and courtship dances. These signals reflect male genetic quality and will be graded by the female to determine a male’s potential as a mate. The stronger the grade, the better the odds of being selected.
But this basic rule isn’t the only yardstick used by females. As surprising as it seems, birds know how to use data from their social environment to maximize their chances of reproduction. Frédérique Dubois, a professor at the Université de Montréal Department of Biological Sciences, has already demonstrated that female Zebra Finches will favour a male chosen by another female. Dubois refers to this as imitation and the use of “public information” in choosing a mate. (more…)
