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Can Inflammation Predict Heart Disease and Stroke?

By Guest PostApril 7, 2012Healthanti inflammatory medication, asthma, blood clots, blood test, c reactive protein, cardiovascular disease, cholesterol, chronic inflammation, crp, disease, heart attack, heart disease, inflammation, protein, stroke

Can Inflammation Predict Heart Disease and Stroke?

Groundbreaking research may be able to help predict how likely it is that a person will have heart disease or a stroke in the future. Studies have linked inflammation to the risk of cardiovascular disease because of the association between the release of C-Reactive Protein (CRP) and heart disease.

What is C-Reactive Protein (CRP)?

The National Institute of Health explains that CRP is a protein that is released when there is inflammation present in the body. The liver produces the protein and a blood test can be done to find out how much CRP is present in a person’s body.

What is inflammation?

John W. Kimball maintains a website describing in depth how inflammation develops in the body. Inflammation develops as a result of injury to the body. It can often be recognized by swelling and redness at the site of inflammation and may be accompanied by pain. Although inflammation often occurs on the surface of the skin, it can also occur internally. (more…)

Curcumin Shows Promise in Attacking Parkinson’s Disease

By Guest PostApril 1, 2012Healthalpha synuclein protein, amino acid, basir ahmad, body temperature, clumping, curcumin, disease, folding, lisa lapidus, parkinson's, protein, spice, technique, turmeric

EAST LANSING, Mich. — Curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson’s disease, says a Michigan State University researcher.

A team of researchers led by Basir Ahmad, an MSU postdoctoral researcher, demonstrated earlier this year that slow-wriggling alpha-synuclein proteins are the cause of clumping, or aggregation, which is the first step of diseases such as Parkinson’s. A new study led by Ahmad, which appears in the current issue of the Journal of Biological Chemistry, shows that curcumin can help prevent clumping. (more…)

The Gene That Can Transform Mild Influenza in to a Life Threatening Disease

By Guest PostMarch 26, 2012Health, Scienceantiviral, cell, deenan pillay, disease, gene variant, genetic finding, greg towers, h1n1 pandemic influenza, hiv, ifitm3 gene, infection, influenza, life threatening, paul kellam, protein, sir mark walport, swine flu, ucl, variant, virus infection

A genetic finding could help to explain why influenza becomes a life-threatening disease for some people, and yet has only a mild effect on others. Collaborative research led by scientists at UCL and the Wellcome Trust Sanger Institute found that people who carry a particular variant of the IFITM3 gene are significantly more likely to be hospitalised when they fall ill with influenza than those who carry other variants.

The gene plays a critical role in protecting the body against infection with influenza and a rare version of it appears to make people more susceptible to severe forms of the disease. The results are published in the journal Nature. (more…)

What Makes Ticks Tick?

By Guest PostMarch 11, 2012Healthanaplasmosis, antibiotic therapy, apple, arthritis, babesiosis, bacterium, climate change, dengue fever, disease, durland fish, european ancestry, evolution, infectious diseases, iPhone, lyme disease, maine, malaria, michigan, minnesota, neurological problems, North America, Pennsylvania, placebo, ticks, united states, virginia, west nile virus, wisconsin

Durland Fish has researched ticks and their associated diseases for decades. A professor in the Division of Epidemiology of Microbial Diseases at the Yale School of Public Health, he has, among other things, contributed to the discovery that the bacterium that causes Lyme disease has European ancestry and that the disease, once nearly eradicated in North America, roared back with reforestation. More recently he helped develop a Lyme disease “app” for the iPhone and other Apple devices that provides users with detailed information about tick populations in any given area in the United States and even comes with a video on how to safely remove a tick. He has also worked on mosquito-borne West Nile virus and dengue fever. Students selected Fish as the school’s mentor of the year in 2010. (more…)

Scientists Pinpoint How Vitamin D May Help Clear Amyloid Plaques Found in Alzheimer’s

By Guest PostMarch 10, 2012Health1a 25 dihydroxyvitamin d3, alzheimer, amyloid beta, amyloid beta protein, antonio barrientos duran, blood, brain, calcium, chemical, chloride channel 3, clc3, component, curcumin, curcuminoids, danusa menegaz, disease, enzymatic conversion, gene, immune cells, immune system, intracellular mechanism, kidneys, liver, macrophages, mathew t mizwicki, milan fiala, patrick r griffin, phagocytosis, plaques, therapy, turmeric spice, vitamin d3

A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer’s disease.

Published in the March 6 issue of the Journal of Alzheimer’s Disease, the early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein. (more…)

Yale Study: How Mitochondrial DNA Defects Cause Inherited Deafness

By Guest PostFebruary 21, 2012Scienceapoptosis, cascade, cell, cellular power plants, cellular respiration, cellular structure, chemical modification, disease, dna mutation, energy, enzyme, gene, gerald s shadel, hearing loss, helen dodson, inherited deafness, justin cotney, lei song, methylation, mitochondria, mitochondrial dna mutation, mitochondrial ribosomes, molecular pathway, mouse model, overexpression, programmed cell death, protein, rna, sharen e mccay, timothy e shutt, yale scientist

Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed cell death. The study is in the Feb. 17 issue of Cell.

Mitochondria are cellular structures that function as “cellular power plants” because they generate most of the cell’s supply of energy. They contain DNA inherited from one’s mother. Mitochondria determine whether a cell lives or dies via the process of programmed cell death, or apoptosis. (more…)

In The Mouth, Smoking Zaps Healthy Bacteria, Welcomes Pathogens

By Guest PostFebruary 20, 2012Healthbacteria, biofilm, bone loss, chad matthews, cytokines, dental plaque, disease, diverse ecosystem, dna signature, ecosystem, gingivitis, good bacteria, harmful bacteria, healthy bacteria, marcelo aspiras, marko de jager, maureen langlois, microbial community, ohio state university, periodontitis, philips oral healthcare, purnimakumar, smokers, smoking, swab, swollen gums, types of cytokines, vinayak joshi

COLUMBUS, Ohio — According to a new study, smoking causes the body to turn against its own helpful bacteria, leaving smokers more vulnerable to disease.

Despite the daily disturbance of brushing and flossing, the mouth of a healthy person contains a stable ecosystem of healthy bacteria. New research shows that the mouth of a smoker is a much more chaotic, diverse ecosystem—and is much more susceptible to invasion by harmful bacteria. (more…)

UCLA Scientists Boost Memory By Stimulating Key Site in Brain

By Guest PostFebruary 16, 2012Sciencealzheimer, americans, barbara knowlton, brain, brain cells, brain site, critical junction, cyber city, disease, entorhinal cortex, eric behnke, hippocampus, itzhak fried, john stern, memory, nanthia suthana, neuro prosthetic devices, neuroscientist, roy mukamel, taxi cab, ucla, united states, video game, virtual passenger, zulfi haneef

*Mechanism holds potential for improving recall in dementia patients*

Have you ever gone to the movies and forgotten where you parked the car? New UCLA research may one day help you improve your memory.

UCLA neuroscientists have demonstrated that they can strengthen memory in human patients by stimulating a critical junction in the brain. Published in the Feb. 9 edition of the New England Journal of Medicine, the finding could lead to a new method for boosting memory in patients with early Alzheimer’s disease. (more…)

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