Tag Archives: brain

Common Parasite May Trigger Suicide Attempts

By Guest PostAugust 18, 2012Health, Scienceamerica, biological change, biological mechanism, brain, brain cell, damage, depression, harmless, infection, inflammation, lena brundin, parasite, parkinsons disease, suicide attempt, symptom, t gondii, teodor postolache, toxoplasma gondii, united states

EAST LANSING, Mich. — A parasite thought to be harmless and found in many people may actually be causing subtle changes in the brain, leading to suicide attempts.

New research appearing in the August issue of The Journal of Clinical Psychiatry adds to the growing work linking an infection caused by the Toxoplasma gondii parasite to suicide attempts. Michigan State University’s Lena Brundin was one of the lead researchers on the team.

About 10-20 percent of people in the United States have Toxoplasma gondii, or T. gondii, in their bodies, but in most it was thought to lie dormant, said Brundin, an associate professor of experimental psychiatry in MSU’s College of Human Medicine. In fact, it appears the parasite can cause inflammation over time, which produces harmful metabolites that can damage brain cells. (more…)

Meditation Reduces Loneliness

By Guest PostAugust 15, 2012Health, Sciencealzheimer's disease, brain, chronic inflammation, crp, david creswell, depression, expression, heart disease, helen lavretsky, immune system, infection, inflammation, inflammatory gene, loneliness, mbsr, meditation, meditative technique, michael irwin, mindfulness, natural component, nf kb, pro inflammatory gene, protein marker, risk, tai chi, yoga

UCLA study also finds that mindfulness technique benefits immune system

Many elderly people spend their last years alone. Spouses pass and children scatter. But being lonely is much more than a silent house and a lack of companionship. Over time, loneliness not only takes a toll on the psyche but can have a serious physical impact as well.

Feeling lonely has been linked to an increased risk of heart disease, Alzheimer’s disease, depression and even premature death. Developing effective treatments to reduce loneliness in older adults is essential, but previous treatment efforts have had limited success. (more…)

Concussions and Head Impacts May Accelerate Brain Aging

By Guest PostAugust 3, 2012Sciencealzheimer, balance, brain, brain aging, brain injury, cognitive decline, concussions, electrical activity, gait, head impacts, kinesiology, lifestyle choice, natural aging, natural deterioration, pothole, signaling pathway, steven broglio, subconcussive impact

ANN ARBOR, Mich.— Concussions and even lesser head impacts may speed up the brain’s natural aging process by causing signaling pathways in the brain to break down more quickly than they would in someone who has never suffered a brain injury or concussion.

Researchers from the University of Michigan School of Kinesiology and the U-M Health System looked at college students with and without a history of concussion and found changes in gait, balance and in the brain’s electrical activity, specifically attention and impulse control, said Steven Broglio, assistant professor of kinesiology and director of the Neurotrauma Research Laboratory. (more…)

Some Harmful Effects of Light at Night Can Be Reversed, Study Finds

By Guest PostJuly 27, 2012Sciencebrain, chronic exposure, depression, depressive disorder, depressive symptom, drug, hamster, harmful effects, hippocampus, light, light cycle, light dark cycle, night, protein, randy nelson, rodent, siberian hamsters, tnf, tnf inhibitor, tracy bedrosian, tumor necrosis factor, xpro1595, zachary weil

COLUMBUS, Ohio – Chronic exposure to dim light at night can lead to depressive symptoms in rodents – but these negative effects can be reversed simply by returning to a standard light-dark cycle, a new study suggests.

While hamsters exposed to light at night for four weeks showed evidence of depressive symptoms, those symptoms essentially disappeared after about two weeks if they returned to normal lighting conditions.

Even changes in the brain that occurred after hamsters lived with chronic light at night reversed themselves after returning to a more normal light cycle. (more…)

Mice Have System to Handle Smell of Fear

By Guest PostJuly 24, 2012Sciencebarnea laboratory, brain, brown university, carnivore, david valenzuela, dheeraj roy, gene expression, gilad barnea, glomeruli, instinctive behavior, lion, lulu tsai, mark a johnson, mice, neuron, olfactory bulb, predator, receptor gene, smell of fear, stavros lomvardas, stephen liberles, subsystem, system, taar, taar proteins, tiger, urine

Mice appear to have a specialized system for detecting and at least initially processing instinctually important smells such as those that denote predators. The finding raises a question about whether their response to those smells is hardwired.

PROVIDENCE, R.I. [Brown University] — A new study finds that mice have a distinct neural subsystem that links the nose to the brain and is associated with instinctually important smells such as those emitted by predators. That insight, published online this week in Proceedings of the National Academy of Sciences, prompts the question whether mice and other mammals have specially hardwired neural circuitry to trigger instinctive behavior in response to certain smells.

In the series of experiments and observations described in the paper, the authors found that nerve cells in the nose that express members of the gene family of trace amine-associated receptors (TAAR) have several key biological differences from the much more common and diverse neurons that express members of the olfactory receptor gene family. Those other nerve cells detect a much broader range of smells, said corresponding author Gilad Barnea, the Robert and Nancy Carney Assistant Professor of Neuroscience at Brown University. (more…)

5 Reasons Your Posture Matters

By Guest PostJuly 6, 2012General, Health, Sports5 reasons, ache, aura, back, better posture, brain, breathing, childhood, confidence, correct posture, good posture, hunching, muscles, nanny jobs, oxygen flow, posture, roxanne porter, self assuredness, self image, shoulder, slouching, spine, stand taller

How many times during your childhood did your mom tell you that you needed to sit or stand up straight or pull your shoulders back as she walked by, and remind you that if you didn’t start having better posture you would end up hunched over for the rest of your life? Whether or not you actually listened, mom may have been on to something when she pulled those shoulders back and forced you to stand taller. Having good posture has a variety of benefits, so the next time you find yourself slouching keep these things in mind:

1. It helps you become more confident: Slouching over or hunching your shoulders makes you look and feel less poised overall, giving off an aura of self-doubt. Simply standing up straighter gives you an air of confidence that can translate into an actual boost in confidence and self-assuredness.

2. Fosters a healthy back and spine: If you sit or stand with bad posture for long enough you’ll start to notice that your back, shoulders, and neck will begin to ache. This is because your spine and back are not meant to be curved over like that. Try standing and sitting up straight instead; you’ll immediately feel better, and your back and spine will thank you. (more…)

Neurons that Control Overeating also Drive Appetite for Cocaine

By Guest PostJune 25, 2012Scienceappetite, behavior, body, brain, brain function, cocaine, cognitive behavior, diabetes, diphtheria toxin, drug addiction, Environment, function, hypothalamus, jeremy bober, jozelia g ferreira, marcelo o dietrich, metabolic disorder, neurons, obesity, overeating, tamas l horvath, transgenic mice

Researchers at Yale School of Medicine have zeroed in on a set of neurons in the part of the brain that controls hunger, and found that these neurons are not only associated with overeating, but also linked to non-food associated behaviors, like novelty-seeking and drug addiction.

Published in the June 24 online issue of Nature Neuroscience, the study was led by Marcelo O. Dietrich, postdoctoral associate, and Tamas L. Horvath, the Jean and David W. Wallace Professor of Biomedical Research and chair of comparative medicine at Yale School of Medicine.

In attempts to develop treatments for metabolic disorders such as obesity and diabetes, researchers have paid increasing attention to the brain’s reward circuits located in the midbrain, with the notion that in these patients, food may become a type of “drug of abuse” similar to cocaine. Dietrich notes, however, that this study flips the common wisdom on its head. (more…)

UCLA Researchers Map Damaged Connections in Phineas Gage’s Brain

By Guest PostMay 18, 2012Science1848 case, alzheimer's disease, andrei irimia, arthur w toga, behavioral change, brain, brain disorder, carinna m torgerson, cerebral cortex, computed tomographic data, emotional function, famous case, frontal temporal dementia, gage skull, history, human connectome project, jack van horn, laboratory, limbic structure, loni, mark wheeler, micah c chambers, microscopic links, model, myelin sheath, nerve fibers, neuro imaging, neurons, neuroscience, phineas gage, railroad, rod, san francisco, skull, south america, trajectory, traumatic brain injury, vermont, white matter

Famous 1848 case of man who survived a terrible accident has modern parallel

Poor Phineas Gage. In 1848, the supervisor for the Rutland and Burlington Railroad in Vermont was using a 13-pound, 3-foot-7-inch rod to pack blasting powder into a rock when he triggered an explosion that drove the rod through his left cheek and out of the top of his head. As reported at the time, the rod was later found, “smeared with blood and brains.”

Miraculously, Gage lived, becoming the most famous case in the history of neuroscience — not only because he survived a horrific accident that led to the destruction of much of his left frontal lobe but also because of the injury’s reported effects on his personality and behavior, which were said to be profound. Gage went from being an affable 25-year-old to one that was fitful, irreverent and profane. His friends and acquaintances said he was “no longer Gage.” (more…)