Tag Archives: brain

‘Explorers’ Use Uncertainty And Specific Area of Brain

*As they try to find the best reward among options, some people explore based on how uncertain they are about the outcome of the options.  Those who employ that thought process, unlike people who use other strategies, uniquely harness the computational power of the rostrolateral prefrontal cortex, a new study finds.*

PROVIDENCE, R.I. [Brown University] — Life shrouds most choices in mystery. Some people inch toward a comfortable enough spot and stick close to that rewarding status quo. Out to dinner, they order the usual. Others consider their options systematically or randomly. But many choose to grapple with the uncertainty head on. “Explorers” order the special because they aren’t sure they’ll like it. It’s a strategy of maximizing rewards by discovering whether as yet unexplored options might yield better returns. In a new study, Brown University researchers show that such explorers use a specific part of their brain to calculate the relative uncertainty of their choices, while non-explorers do not. (more…)

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Men More Likely To Have An Accurate Memory of Unpleasant Experiences

A woman’s memory of an experience is less likely to be accurate than a man’s if it was unpleasant and emotionally provocative, according to research undertaken by University of Montreal researchers at Louis-H Lafontaine Hospital. “Very few studies have looked at how ‘valence’ and ‘arousal’ affect memories independently of each other, that is to say, how attractive or repulsive we find an experience and how emotionally provocative it is,” said corresponding author Dr. Marc Lavoie, of the university’s Department of Psychiatry and the hospital’s Fernand-Seguin Research Center. “Our test relied on photos – we found firstly that highly arousing pictures blur women’s capacity to determine whether they’ve seen it before, and secondly that women have a clearer memory of attractive experiences than men. Arousal has an enhancing effect on the memory of men however, as does ‘low valence’ or unpleasantness.” (more…)

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A Whole New Meaning for Thinking on Your Feet

Smithsonian researchers report that the brains of tiny spiders are so large that they fill their body cavities and overflow into their legs. As part of ongoing research to understand how miniaturization affects brain size and behavior, researchers measured the central nervous systems of nine species of spiders, from rainforest giants to spiders smaller than the head of a pin. As the spiders get smaller, their brains get proportionally bigger, filling up more and more of their body cavities.

“The smaller the animal, the more it has to invest in its brain, which means even very tiny spiders are able to weave a web and perform other fairly complex behaviors,” said William Wcislo, staff scientist at the Smithsonian Tropical Research Institute in Panama. “We discovered that the central nervous systems of the smallest spiders fill up almost 80 percent of their total body cavity, including about 25 percent of their legs.” (more…)

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Ovarian Cancer Study Proves Drug Delays Disease Progression

*U of T, U.K. study focused on Avastin*

Treating ovarian cancer with the drug bevacizumab (“Avastin”) delays the disease and may also improve survival, according to an international clinical trial co-led by Drs. Amit Oza of the University of Toronto and Princess Margaret Hospital (PMH) and Timothy Perren of St James’s Institute of Oncology, Leeds, U.K.

The findings, published on Dec. 28 in the New England Journal of Medicine, report that the drug halted the cancer’s return for two months overall. However, for women with the highest risk disease, the delay was five to six months and in this group, the findings also indicate a strong trend to improved overall survival, which is being analysed until 2013. (more…)

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Yale Researchers Find Genetic Link Between Heart Disease and Brain Aneurysms

Yale School of Medicine researchers have discovered that a variant of a gene linked to heart disease also increases the risk of deadly aneurysms of blood vessels in the brain. The discovery of this link raises hopes for new treatments for intracranial aneurysms, which affect more than a half million people worldwide annually.

“Existing drugs already target this common pathway and, in the future, could help treat or prevent aneurysms in people who are at risk,” said Murat Gunel, professor of neurosurgery, genetics and neurobiology and senior author of the study, published the week of Nov. 21 in the Proceedings of the National Academy of Sciences. (more…)

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Research Sheds New Light on Body Parts’ Sensitivity to Environmental Changes

EAST LANSING, Mich. — Research by a team of Michigan State University scientists has shed new light on why some body parts are more sensitive to environmental change than others, work that could someday lead to better ways of treating a variety of diseases, including Type-2 diabetes.

The research, led by assistant zoology professor Alexander Shingleton, is detailed in the recent issue of the Proceedings of the Library of Science Genetics. (more…)

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At a Loss for Words

*Research into aphasia – the inability to speak or write well-formulated sentences and words – is strong at the UA. Researchers have received $2 million toward the study of the condition.*

The National Institutes of Health have awarded the University of Arizona’s Aphasia Research Project in the department of speech, language and hearing sciences a $2 million grant to research communication impairments in adults who have suffered brain injury.

Aphasia – the inability to speak or write well-formulated sentences and words – is a common result of a stroke or a traumatic brain injury such as the one suffered by Rep. Gabrielle Giffords, who was shot in the head earlier this year. The bullet damaged regions of the brain that are critical for language and control of the right side of the body. (more…)

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How the Brain Makes Memories: Rhythmically!

The brain learns through changes in the strength of its synapses — the connections between neurons — in response to stimuli.

Now, in a discovery that challenges conventional wisdom on the brain mechanisms of learning, UCLA neuro-physicists have found there is an optimal brain “rhythm,” or frequency, for changing synaptic strength. And further, like stations on a radio dial, each synapse is tuned to a different optimal frequency for learning.

The findings, which provide a grand-unified theory of the mechanisms that underlie learning in the brain, may lead to possible new therapies for treating learning disabilities. (more…)

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