EAST LANSING, Mich. — A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists.
A team led by Dana Spence of MSU’s Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1. By creating a new, simple method to study it after blood is drawn, the team has unlocked a potential new drug target for many diseases that impact red blood cells, such as diabetes, hypertension and cystic fibrosis. (more…)
*A 33,000-year-old dog skull unearthed in a Siberian mountain cave presents some of the oldest known evidence of dog domestication and, together with an equally ancient find in a cave in Belgium, indicates that modern dogs may be descended from multiple ancestors.*
If you think a Chihuahua doesn’t have much in common with a Rottweiler, you might be on to something.
An ancient dog skull, preserved in a cave in the Altai Mountains of Siberia for 33,000 years, presents some of the oldest known evidence of dog domestication and, together with equally ancient dog remains from a cave in Belgium, indicates that domestication of dogs may have occurred repeatedly in different geographic locations rather than with a single domestication event. (more…)
*Engineers at Brown University have designed a biological device that can measure glucose concentrations in human saliva. The technique could eliminate the need for diabetics to draw blood to check their glucose levels. The biochip uses plasmonic interferometers and could be used to measure a range of biological and environmental substances. Results are published in Nano Letters.*
PROVIDENCE, R.I. [Brown University] — For the 26 million Americans with diabetes, drawing blood is the most prevalent way to check glucose levels. It is invasive and at least minimally painful. Researchers at Brown University are working on a new sensor that can check blood sugar levels by measuring glucose concentrations in saliva instead.
The technique takes advantage of a convergence of nanotechnology and surface plasmonics, which explores the interaction of electrons and photons (light). The engineers at Brown etched thousands of plasmonic interferometers onto a fingernail-size biochip and measured the concentration of glucose molecules in water on the chip. Their results showed that the specially designed biochip could detect glucose levels similar to the levels found in human saliva. Glucose in human saliva is typically about 100 times less concentrated than in the blood. (more…)
Minuscule amounts of ethanol, the type of alcohol found in alcoholic beverages, can more than double the life span of a tiny worm known as Caenorhabditiselegans, which is used frequently as a model in aging studies, UCLA biochemists report. The scientists said they find their discovery difficult to explain.
“This finding floored us — it’s shocking,” said Steven Clarke, a UCLA professor of chemistry and biochemistry and the senior author of the study, published Jan. 18 in the online journal PLoS ONE, a publication of the Public Library of Science. (more…)
COLUMBUS, Ohio – For students to accept the theory of evolution, an intuitive “gut feeling” may be just as important as understanding the facts, according to a new study.(more…)
ANN ARBOR, Mich.— Astronomers have detected a mysterious ring of carbon monoxide gas around the young star V1052 Cen, which is about 700 light years away in the southern constellation Centaurus.(more…)
Many infections, even those caused by antibiotic-sensitive bacteria, resist treatment. This paradox has vexed physicians for decades, and makes some infections impossible to cure.(more…)
Lived in the ocean more than 500-million years ago
A bizarre creature that lived in the ocean more than 500-million years ago has emerged from the famous Middle Cambrian Burgess Shale in the Canadian Rockies.(more…)
